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Shaik Sarfaraz Nawaz

Researcher

Researcher

كلية الطب
Strategic Center for Diabetes Research, College of Medicine, King Saud University
المنشورات
مقال فى مجلة
2019

IL-18, VCAM-1 and P-selectin as early biomarkers in normoalbuminuric Type 2 diabetes patients

, ,Khalid Al-Rubeaan, Shaik S Nawaz, Amira M Youssef, Mohammed Al Ghonaim & Khalid Siddiqui . 2019

Aim: To investigate the pathophysiological role of different biomarkers in diabetic kidney disease (DKD) among normoalbuminuric patients with a low-estimated glomerular filtration rate (eGFR). Methods: In this cross-sectional study of 200 normoalbuminuric Type 2 diabetes patients, 28 patients (14%) had a low eGFR. Results: The IL-18, VCAM-1 and P-selectin levels were significantly higher at a low eGFR. On analyzing the area under the receiver operating characteristic curve, these biomarkers had significant diagnostic value and have important pathophysiological role in the progression of DKD. Conclusion: Among normoalbuminuric Type 2 diabetes patients, IL-18, VCAM-1 and P-selectin may play a significant role in the prediction of early DKD. Further prospective studies need to be conducted to confirm this observation.

نوع عمل المنشور
Original Researc
رقم المجلد
13
مجلة/صحيفة
BIOMARKERS IN MEDICINE
مزيد من المنشورات
publications

Abstract

بواسطة K Siddiqui, TP George, SS Joy, SS Nawaz,
2020
تم النشر فى:
The Journal of Maternal-Fetal & Neonatal Medicine
publications

Metabolomics is rapidly evolving omics technology in personalized medicine, it offers a new avenue for identification of multiple novel metabolic mediators of impaired glucose tolerance and…

بواسطة S Chowdhury, SM Faheem, SS Nawaz, K Siddiqui,
2021
تم النشر فى:
Personalized Medicine