Saudi Clinical Practice Guideline on Management of ST-elevation myocardial infarction.
This practice guideline is a part of the larger
initiative of the Ministry of Health of the King-
dom of Saudi Arabia to establish a program of
rigorous development of guidelines. The ulti-
mate goals are to provide guidance for clini-
cians and other healthcare decision makers
and reduce unnecessary variability in clinical
practice across the Kingdom.
The Saudi expert guideline panel selected the
topic of this guideline and all healthcare ques-
tions addressed herein using a formal prioriti-
zation process. For all selected questions we
updated existing systematic reviews on myo-
cardial infarction with ST-segment elevation
published in July 2013 by the National Clinical
Guideline Centre for the National Institute for
Health and Care Excellence (NICE).
4
We also
conducted systematic searches for infor-
mation that was required to develop full
guidelines for the KSA, including searches for
information about patients’ values and pref-
erences, and costs and resource use specific
to the Saudi context. Based on the systematic
reviews we prepared summaries of available
evidence supporting each recommendation
following the GRADE (Grading of Recommen-
dations, Assessment, Development and Evalu-
ation) approach.
5
We used this information to
prepare GRADE evidence-to-decision frame-
works that served the guideline panel to fol-
low the structured consensus process and
transparently document all decisions made
during the meeting (see Appendix 1). The
guideline panel met in Riyadh on March 15 &
16, 2015 and formulated all recommendations
during this meeting. Potential conflicts of in-
terests of all panel members were managed
according to the World Health Organization
(WHO) rules.
6
