The term epigenetics refers to heritable changes in gene expression (active versus inactive genes) that does not involve changes to the underlying DNA sequence; a change in phenotype without a change in genotype. Epigenetic change is a regular and natural occurrence but can also be influenced by several factors including age, the environment/lifestyle, and disease state. Epigenetic modifications can manifest as commonly as the manner in which cells terminally differentiate to end up as skin cells, liver cells, brain cells, etc. Or, epigenetic change can have more damaging effects that can result in diseases like cancer. New and ongoing research is continuously uncovering the role of epigenetics in a variety of human disorders and fatal diseases


Thursday, September 12, 2019 - 08:59
The main objective of this course is to provide knowledge about the fundamental aspects of genetic diseases, their classification, modes of inheritance, population genetics and genetic...
DNA Methylation Chapter, Publisher by InTech, ISBN 978-953-51-2030-8, PP 27-56, 2015. (More than 1000 International downloaded)