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Dr. Motiur Rahman

Associate Professor

Pharmaceutical Chemistry, College of Pharmacy

كلية الصيدلة
Room no. 2A118, Building 23, Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University
المنشورات
مقال فى مجلة

Journal Article

43. <strong>A. F. M. Motiur Rahman,* </strong>Wencui Yin, Adnan A. Kadi, Yurngdong Jahng. Galeon: A Biologically Active Molecule with In Silico Metabolite Prediction, In Vitro Metabolic Profiling in Rat Liver Microsomes, and In Silico Binding Mechanisms with CYP450 Isoforms, Molecules, <strong>2020</strong>, 25, 5903; doi.org/10.3390/molecules25245903, <strong>Impact factor = 3.27</strong><br />
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42. Hany W Darwish, Ahmed H Bakheit, Nasser S Al-Shakliah, <strong>A. F. M. Motiur Rahman</strong>, Ibrahim A Darwish. Experimental and computational evaluation of kolliphor RH 40 as a new fluorescence enhancer in development of a micellar-based spectrofluorimetric method for determination of lapatinib in tablets and urine. Plos one, <strong>2020</strong>, 15(12), e0239918; doi.org/10.1371/journal.pone.0239918, <strong>Impact factor = 2.75</strong><br />
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41. Huda S. Alsalem,* Md Arifuzzaman, Hamad M. Alkahtani, Ashraf N. Abdalla, Iman S. Issa, Aljawharah Alqathama, Fatemah S. Albalawi and <strong>A.F.M. Motiur Rahman*</strong>. A Series of Isatin-Hydrazones with Cytotoxic Activity and CDK2 Kinase Inhibitory Activity: A Potential Type II ATP Competitive Inhibitor, Molecules, <strong>2020</strong>, 25, 4400; doi:10.3390/molecules25194400, <strong>Impact factor = 3.27</strong><br />
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40. Huda S. Alsalem,* Hatem A. Abuelizz, Iman S. Issa, Amany Z. Mahmoud, Ali Al-Hoshani, Md Arifuzzaman and <strong>A.F.M. Motiur Rahman*.</strong> Synthesis of Novel Potent Biologically Active&nbsp;N-Benzylisatin-Aryl Hydrazones in Comparison with Lung Cancer Drug ‘Gefitinib’, <a href="https://www.mdpi.com/journal/applsci&quot; target="_blank">Applied Sciences</a>, <strong>2020</strong>,&nbsp;10(11), 3669; https://doi.org/10.3390/app10113669), <strong>Impact factor = 2.217</strong><br />
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39. Mohammad Shahidul Islam, Abdullah Mohammed Al-Majid, Fardous F. El-Senduny, Farid A. Badria, <strong>A. F. M. Motiur Rahman</strong>, Assem Barakat and Yaseen A. M. M. Elshaier, Synthesis, Anticancer Activity, and Molecular Modeling of New Halogenated Spiro[pyrrolidine-thiazolo-oxindoles] Derivatives, <a href="https://www.mdpi.com/journal/applsci&quot; target="_blank">Applied Sciences</a>, <strong>2020</strong>, 10(6), 2170<strong> (</strong>doi.org/10.3390/app10062170), <strong>Impact factor = 2.217</strong><br />
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38. Yang Lu, Wencui Yin, Mohammad Sayed Alam, Adnan A. Kadi, Yurngdong Jahng, Youngjoo Kwon, <strong>A. F. M. Motiur Rahman,</strong> Synthesis, Biological Evaluation, Binding Interaction and Drug Likeness Property Analysis of Cyclic Diarylheptanoids as Potential Anticancer Therapeutics, Anti-Cancer Agents in Medicinal Chemistry, <strong>2020</strong>, 20(4), 464-475 (<a href="https://doi.org/10.2174/1871520619666191125130237&quot; target="_blank">10.2174/1871520619666191125130237</a>), <strong>Impact factor = 2.18</strong><br />
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37. Mohsin Kazi, Fahad Almarri, Muhammad Yousaf, Mohammad Nur-e-Alam, <strong>A F M Motiur Rahman</strong> and Fars K. Alanazi, Simultaneous determination of cholecalciferol and 25-2 hydroxycholecalceferol in lipid-based self-nanoemulsifying formulations and marketed product vi-de 3 3 ® by uhplc-uv” Current Pharmaceutical Analysis, <strong>2020</strong>, 16(1), 100-109 (<a href="https://doi.org/10.2174/1573412915666190612141228&quot; target="_blank">10.2174/1573412915666190612141228</a>), <strong>Impact factor = 0.829</strong><br />
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36. Adnan A. Kadi, Kamal E.H. El-Tahir,* Yurngdong Jahng, <strong>A.F.M. Motiur Rahman</strong>,* Synthesis, Biological Evaluation and Structure Activity Relationships (SARs) Study of 8-(Substituted)aryloxycaffein, Arabian Journal of Chemistry, <strong>2019</strong>, 12(8), 2356-2364 (doi:10.1016/j.arabjc.2015.02.021). (<strong>Impact factor = 3.298</strong>)<br />
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35. Abdullah Mohammed Al-Majid, Mohammad Shahidul Islam, Saleh Atef,&nbsp;<br />
Fardous F. El-Senduny, Farid A. Badria, Yaseen A. M. M. Elshaier, M. Ali,&nbsp;<br />
Assem Barakat, <strong>A. F. M. Motiur Rahman</strong>, Synthesis of pyridine-dicarboxamide-cyclohexanone derivatives: Anti-cancer and α-glucosidase inhibitory activities and in silico study, Molecules, <strong>2019</strong>, 24, 1332 (doi:10.3390/molecules24071332), <strong>Impact factor = 3.1</strong><br />
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34. Adnan A. Kadi, Wencui Yin and <strong>A. F. M. Motiur Rahman</strong>, <a href="https://www.evise.com/evise/faces/pages/homepage/homepage.jspx?_adf.ctr…; title="In-Vitro Metabolic Profiling Study of Potential Topoisomerase Inhibitors ‘Pyrazolines’ in RLMs by Mass Spectrometry ">In-Vitro Metabolic Profiling Study of Potential Topoisomerase Inhibitors ‘Pyrazolines’ in RLMs by Mass Spectrometry</a>, Journal of Chromatography B, <strong>2019</strong>, 1114-1115, 125-133.(https://doi.org/10.1016/j.jchromb.2019.03.026), <strong>Impact factor = 2.441</strong><br />
33.<strong> A. F. M. Motiur Rahman</strong>, Yang Lu, Hwa-Jong Lee, Hyunji Jo, Wencui Yin, Mohammad Sayed Alam, Hyochang Cha, Adnan A. Kadi, Youngjoo Kwon, Yurngdong Jahng. Linear Diarylhepatonoids: Synthesis, Biological Evaluation and SARs Studies as Potential Anticancer Therapeutics. <a href="https://link.springer.com/journal/12272&quot; title="Archives of Pharmacal Research">Archives of Pharmacal Research</a>, <strong>2018</strong>, 41(12):1131-1148 (https://doi.org/10.1007/s12272-018-1004-8). (<strong>Impact factor = 2.324</strong>)<br />
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32. Adnan A. Kadi, Nasser S. Al-Shakliah, Wencui Yin, <strong>A.F.M. Motiur Rahman. </strong><a href="http://www.sciencedirect.com/science/article/pii/S1570023216314015">In vitro&nbsp;Investigation of Metabolic Profiling of Newly Developed Topoisomerase Inhibitors (Ethyl Fluorescein Hydrazones) in RLMs by LC–MS/MS</a>. Journal of Chromatography B, 2017, <strong>2017</strong>, 1054, 93-101, (http://doi.org/10.1016/j.jchromb.2017.03.042). (<strong>Impact factor = 2.603</strong>)<br />
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31. <strong>A.F.M. Motiur Rahman</strong>, Nasser S. Al-Shakliah, Wencui Yin, Adnan A. Kadi. <a href="http://www.sciencedirect.com/science/article/pii/S1570023216314143">In vitro&nbsp;investigation of metabolic profiling of a potent topoisomerase inhibitors fluorescein hydrazones (FLHs) in RLMs by LC–MS/MS</a>. Journal of Chromatography B, <strong>2017</strong>, 1054, 27-35, (http://doi.org/10.1016/j.jchromb.2017.03.041). (<strong>Impact factor = 2.603</strong>)<br />
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30. Yang&nbsp;Lu, <strong>A.&nbsp;F.&nbsp;M.&nbsp;Motiur Rahman</strong>, Yurngdong&nbsp;Jahng. Studies on the reactions of 3,2′-polymethylene-2-phenylbenzo[b]-1,10-phenanthrolines with Ru(tpy)Cl3and properties of the products. <a href="https://link.springer.com/journal/12272&quot; title="Archives of Pharmacal Research">Archives of Pharmacal Research</a>, <strong>2017</strong>, 40, 563-570 (10.1007/s12272-017-0894-1). (<strong>Impact factor = 2.324</strong>)<br />
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29. Islam, M. S.; Park, S.; Song, C.; Kadi, A. A.; Kwon, Y.; <strong>Rahman, A. F. M. Motiur.</strong> Fluorescein hydrazones: A series of novel non-intercalative topoisomerase IIα catalytic inhibitors induce G1 arrest and apoptosis in breast and colon cancer cells. European Journal of Medicinal Chemistry, <strong>2017</strong>, 125, 49-67 (http://dx.doi.org/10.1016/j.ejmech.2016.09.004). (<strong>Impact factor = 4.519</strong>)<br />
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28. Pervez Ahmad, Hyunjung Woob, Kyu-Yeon Junb, Adnan A. Kadi, Hatem A. Abdel-Aziza, Youngjoo Kwonb, <strong>A. F. M. Motiur Rahman</strong>, Design, synthesis, topoisomerase I &amp; II inhibitory activity, antiproliferative activity, and structure-​activity relationship study of pyrazoline derivatives: An ATP- competitive human topoisomerase IIα catalytic inhibitor, Bioorganic &amp; Medicinal Chemistry, <strong>2016, </strong>24, 1898-1908 (http://dx.doi.org/10.1016/j.bmc.2016.03.017). (<strong>Impact factor = 2.930</strong>)&nbsp;<br />
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27. <a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Moh… Shahidul Islam</a>,&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Ass… Barakat</a>,&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Abd… M. Al-Majid</a><a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274#af00…; title="Affiliation: a">a</a>,&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Haz… A. Ghabbour</a>, <a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274"><st…. Motiur Rahman</strong></a>, <a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Kul… Javaid</a>,&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Reh… Imad</a>,&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">Sam… Yousuf</a>,&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/S0968089616301274">M. Iqbal Choudhary</a>, A concise synthesis and evaluation of new malonamide derivatives as potential α-glucosidase inhibitors, Bioorganic &amp; Medicinal Chemistry, <strong>2016</strong>, 24, 1675-1682 (http://dx.doi.org/10.1016/j.bmc.2016.02.037). (<strong>Impact factor = 2.930</strong>)<br />
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26. &nbsp;<strong>A. F. M. Motiur Rahman</strong> and Adnan A Kadi, Solvent free Cannizzaro reaction applying grindstone technique, Arabian Journal of Chemistry, <strong>2016, </strong>9(2), S1373-S1377, http://dx.doi.org/10.1016/j.arabjc.2012.02.010). (<strong>Impact factor = 4.553</strong>)<br />
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25. Adnan A. Kadi, Nasser S. Al-Shakliah, <strong>A. F</strong><strong>. M. Motiur Rahman</strong>,* Synthesis and Fragmentation Behavior Study of n-alkyl/benzyl Isatin Derivatives Present in Small/Complex Molecules: Precursor for the Preparation of Biological Active Heterocycles, Mass Spectrometry Letters, <strong>2015</strong>, 6(3), 65-70 (doi: 10.5478/MSL.2015.6.3.65).<br />
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24. <strong>A.F.M. Motiur Rahman</strong>,* Rihab F. Angawi, Adnan A. Kadi, Spatial Localization of Curcumin and Rapid Screening of the Chemical Compositions of Turmeric Rhizomes (Curcuma longa Linn.) using Direct Analysis in Real Time-Mass Spectrometry (DART-MS), Food Chemistry<em>, </em><strong>2015</strong>, <em>173</em>, 489–494, (<a href="http://dx.doi.org/10.1016/j.foodchem.2014.10.049">http://dx.doi.org/10…;). (<strong>Impact factor = 4.529</strong>)<br />
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23. <strong>A. F. M. Motiur Rahman</strong>,* So-Eun Park, Adnan A. Kadi, and Youngjoo Kwon, Fluorescein Hydrazones as Novel Nonintercalative Topoisomerase Catalytic Inhibitors with Low DNA Toxicity, Journal of Medicinal Chemistry <strong>2014</strong>, 57, 9139−9151 (doi: dx.doi.org/10.1021/jm501263m). (<strong>Impact factor = 6.259</strong>)<br />
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22. Adnan A. Kadi, Mohamed W. Attwa, <strong>A. F. M. Motiur Rahman</strong>,<strong>*</strong> A Preliminary Study of Arecoline and Guvacoline Presence in Saliva of ‘Betel-Quid’ Chewer Using Liquid-Chromatography Ion Trap Mass Spectrometry, European Journal of Mass Spectrometry, <strong>2013</strong>, 19, 391-397 (doi: 10.1255/ejms.1245). (<strong>Impact factor = 1.022</strong>)<br />
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21. <strong>A. F. M. Motiur Rahman</strong>, Mohamed W. Attwa, Pervez Ahmad, Mohammad Baseeruddin, Adnan A. Kadi; Fragmentation Behavior Studies of Chalcones Employing Direct Analysis in Real Time (DART), Mass Spectrometry Letters, <strong>2013</strong>, 4(2), 30-33.<br />
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20. Mazlin Mohideen, Nik Salmah Nik-Salleh, Suraya Zulkepli, Mohd Zulkefeli, J. F. F. Weber, <strong>A. F. M. Motiur Rahman</strong>,*Design, synthesis, in vitro cytotoxicity evaluation and structure–activity relationship of Goniothalamin analogs, Archives of Pharmacal Research, <strong>2013</strong>, 36 (7), 812-831 (doi:10.1007/s12272-013-0099-1). (<strong>Impact factor = 2.324</strong>)<br />
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19. <strong>A. F. M. Motiur Rahman</strong> Hyochang Cha, Kyungsook Kwak, Eung-Seok Lee, Yurngdong Jahng, Racemization Energy of 3,2''-Tetramethylene-2-phenyl-6-(pyrid-2''''-yl)pyridine Estimated by Temperature Variation 1H NMR Experiment, Bulletin of the Korean Chemical Society, <strong>2013</strong>, 34 (2), 677-679 (http://dx.doi.org/10.5012/bkcs.2013.34.2.677). (<strong>Impact factor = 0.602</strong>)<br />
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18. <strong>A. F. M. Motiur Rahman</strong>, Mohammad Sayed Alam and Adnan A. Kadi, Synthesis and antimicrobial activity of novel tetrabromo- α,α′-bis(substituted-benzyl)cycloalkanones, Journal of the Serbian Chemical Society, J. Serb. Chem. Soc. <strong>2012</strong>, 77 (6) 717-723, (doi: 10.2298/JSC110408005M). (<strong>Impact factor = 0.822</strong>)<br />
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17. <strong>A. F. M. Motiur Rahman</strong>, Roushown Ali, Yurngdong Jahng and Adnan A. Kadi, A Facile Solvent Free Claisen-Schmidt Reaction: Synthesis of α,α′-bis-(Substituted-benzylidene)cycloalkanones and α,α′-bis-(Substituted-alkylidene)cycloalkanones, Molecules, <strong>2012</strong>, 17 (1), 571-583, (doi:<a href="http://dx.doi.org/10.3390/molecules17010571">10.3390/molecules17010571<…;). (<strong>Impact factor = 2.861</strong>)<br />
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16. <strong>A. F. M. Motiur Rahman</strong> and Yurngdong Jahng, Synthesis of 8-aryloxycaffeines and their inhibitory activities on topoisomerase II, Yakhak Hoeji <strong>2011</strong>, 55 (6), 441-445.<br />
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15. Yurngdong Jahng, <strong>A. F. M. Motiur Rahman</strong>, Synthesis and Properties of 2,2'-Di(heteroaryl)-9,9'-spirobifluorenes,&nbsp; Bulletin of the Chemical Society of Japan,<strong> 2010</strong>, 83 (6), 672-677 (doi: 10.1246/bcsj.20090121). (<strong>Impact factor = 0.602</strong>)<br />
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14. Yurngdong Jahng, Young Hwan Hong, and <strong>A.F.M. Motiur Rahman</strong>, Synthesis and properties of ruthenium(II) complexes of 3,3'-polymethylene-2-(pyrid-2'-yl)benzo[ b ]-1,10-phenanthrolines, Journal of Coordination Chemistry, <strong>2010</strong>, 63 (10), 1774-1784 (<strong>doi:</strong>10.1080/00958972.2010.487101). (<strong>Impact factor = 1.795</strong>)<br />
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13. Dong Hyeon Kim, <strong>A. F. M. Motiur Rahman</strong>, Byeong-Seon Jeong, Eung Seok Lee and Yurngdong Jahng, Acetate-Promoted Aldol-Type Reaction: Scope and Reactivity of Acetates and Aldehydes. Bull. Korean Chem. Soc. 30(4), 797-802, <strong>2009 </strong>(<strong>doi:</strong> <a href="http://dx.doi.org/10.5012/bkcs.2009.30.4.797&quot; target="_blank">http://dx.doi.org/10.5012/bkcs.2009.30.4.797</a&gt;). (<strong>Impact factor = 0.602</strong>)<br />
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12. <strong>A. F. M. Motiur Rahman</strong>, Dong Hyeon Kim, Jing Lu Liang, Eung-Seok Lee, Younghwa Na, Kyu-Yeon Jun, Youngjoo Kwon, and Yurngdong Jahng, Synthesis and Biological Properties of Luotonin A Derivatives. Bull. Korean Chem. Soc. 29(10), 1988-1992, <strong>2008 </strong>(<strong>doi:</strong> <a href="http://dx.doi.org/10.5012/bkcs.2008.29.10.1988&quot; target="_blank">http://dx.doi.org/10.5012/bkcs.2008.29.10.1988</a&gt;). (<strong>Impact factor = 0.602</strong>)<br />
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11. <strong>A. F. M. Motiur Rahman</strong>, Jing Lu Liang, Seung Ho Lee, Jong Keun Son, Mi-Ja Jung, Youngjoo, Kwon, and Yurngdong Jahng, 2,2-Dimethyl-2<em>H</em>-pyran-Derived Alkaloids I. Practical Synthesis of Acronycine and Benzo[<em>b</em>]acronycine and Their Biological Properties. Arch. Pharm. Res. 31(9), 1087-1093, <strong>2008 </strong>(doi: 10.1007/s12272-001-1273-7). (<strong>Impact factor = 2.324</strong>)<br />
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10. <strong>A. F. M. Motiur Rahman </strong>and Yurngdong Jahng, Benzo[b]-1,10-Phenanthrolines. V. Synthesis and Properties of 3,3’-Polymethylene-2-(pyrid-2’-yl)benzo[b]1,10-phenanthrolines. Heterocycles, 75(10), 2507-12, <strong>2008 </strong>(doi: 10.3987/COM-08-11423). &nbsp;(<strong>Impact factor = 0.805</strong>)<br />
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9.&nbsp; <strong>A. F. M. Motiur Rahman </strong>and Yurngdong Jahng, Synthesis and Properties of 3,3’-Polymethylene-2,2’-bibenzo[b]1,10-phenanthrolines. Heterocycles, 75(4), 871-77 (doi: 10.3987/COM-07-11281), <strong>2008</strong>. (<strong>Impact factor = 0.805</strong>)<br />
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8.&nbsp;&nbsp; Hee Wook Jung, Joon Seok Oh, Seung Ho Lee, Jiang Lu Liang, Dong Hyeon Kim, <strong>A. F. M. Motiur Rahman</strong>, and Yurngdong Jahng, A Facile Synthesis of Mollugin, Bull. Korean Chem. Soc. 28 (10), 1863-66, <strong>2007 (<strong>doi:</strong></strong> <a href="http://dx.doi.org/10.5012/bkcs.2007.28.10.1863&quot; target="_blank">http://dx.doi.org/10.5012/bkcs.2007.28.10.1863</a&gt;). (<strong>Impact factor = 0.602</strong>)<br />
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7.&nbsp; <strong>A. F. M. Motiur Rahman </strong>and Yurngdong Jahng, Synthesis and Properties of Benzo[b]-1,10-Phenanthrolines and Their Metal Complexes, Heteroatom Chemistry, 18(6), 650-56, <strong>2007 </strong>(doi:&nbsp;10.1002/hc.20358). (<strong>Impact factor = 1.221</strong>)<br />
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6.&nbsp; <strong>A. F. M. Motiur Rahman </strong>and Yurngdong Jahng, Synthesis and Properties of 3,2’-Polymethylene-2-phenylbenzo[b]phenanthrolines. Heterocycles, 71(9), 2003-10, <strong>2007 </strong>(doi: 10.3987/COM-07-11094). (<strong>Impact factor = 0.805</strong>)<br />
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5<strong>.&nbsp; A. F. M. Motiur Rahman</strong>, Byeong-Seon Jeong, Dong Hyeon Kim, Jung Ki Park, Eung Seok Lee and Yurngdong Jahng, A facile synthesis of α,α′-bis(substitutedbenzylidene)-cycloalkanones and substituted-benzylidene heteroaromatics: utility of NaOAc as a catalyst for aldol-type reaction. Tetrahedron, 63 (11), 2426-31, <strong>2007 </strong>(doi.org/10.1016/j.tet.2007.01.020). (<strong>Impact factor = 2.651</strong>)<br />
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4. <strong>A. F. M. Motiur Rahman </strong>and Yurngdong Jahng, Preparation of Geminal Diacylates (Acylals) of Aldehyde-Scope and Reactivity of Aldehyde with Acid Anhydride. European Journal of Organic Chemistry, 2, 379-83, <strong>2007 </strong>(doi:&nbsp;10.1002/ejoc.200600737). (<strong>Impact factor = </strong><strong>2.834</strong>)<br />
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3. <strong>A. F. M. Motiur Rahman </strong>and Yurngdong Jahng, Simple Synthesis of Geminal Diacetates (Acylals) of Aromatic Aldehydes. Synthetic Communications, 36 (9), 1213-20, <strong>2006 </strong>(<strong>doi:</strong>10.1080/00397910500514154). (<strong>Impact factor = 1.134</strong>)<br />
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2.&nbsp; <strong>A. F. M. Motiur Rahman</strong>, Youngjoo Kwon, and Yurngdong Jahng, Friedländer Reactions of Triacetylmethane –Unusual Distribution of Products. Heterocycles, 65 (11), 2777–82, <strong>2005 </strong>(doi: 10.3987/COM-05-10534). (<strong>Impact factor = 0.805</strong>)<br />
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1.&nbsp; H. N. Roy, <strong>A. F. M. M. Rahman </strong>and M. A. Islam, Regiospecific synthesis of carboxylated &amp;&nbsp; simple α-tetralones with homophthalates and various acrylates by simple condensation method.&nbsp; Journal of Chemical Research (S), 594-96, <strong>2003 </strong>(<strong>doi:</strong> <a href="http://dx.doi.org/10.3184/030823403322597766">http://dx.doi.org/10.3184…;). (<strong>Impact factor = 0.646</strong>)

مزيد من المنشورات
publications

43. <strong>A. F. M. Motiur Rahman,* </strong>Wencui Yin, Adnan A. Kadi, Yurngdong Jahng.

publications

4. Simple synthesis and Biological Properties of Goniothalamin, The Fourth International Chemistry Conferences, 2011, November 19-21, Riyadh, Saudi Arabia

3. Improved Synthesis and…

publications

35. Adnan A Kadi; Nasser S. Al-Shakliah; Youngjoo Kwon; A. F. M. Motiur Rahman. In vitro Investigation of Metabolic Profiling of Newly Developed Topoisomerase Inhibitors (Ethyl Fluorescein…