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Ahmed Hossam Mahmoud

Associate Professor

أستاذ مشارك

كلية العلوم
2b 162
المنشورات
مقال فى مجلة
2017

Impacts of restricted feeding and realimentation on bone development and plasma concentrations of bone-specific biomarkers in lambs

mahmoud, A. . 2017

feed restriction bone length phosphorus osteocalcin lambs

 ABSTRACT. The aim of the study was to assess the effect of feed restriction levels followed by realimentation on long bone growth and concentrations of growth hormone, osteocalcin, bone-specific alkaline phosphatase (ALP), cal­cium (Ca) and phosphorus (P) in plasma. Thirty-six Najdi ram lambs weighing 30.1 ± 0.3 kg were randomly allotted to one of three feeding regimens. The first group was fed ad libitum throughout the trial (AD group). Other groups were subjected to 5-week feed restriction at either 0.75 or 0.60 of ad libitum intake (0.75AD and 0.60AD groups, respectively). Following the restriction pe­riod, lambs were returned to ad libitum feeding (realimentation) for 7 weeks. Feed restriction suppressed (P < 0.01) the growth of bone lengths in proportion to the restriction level. After the realimentation, bone lengths of animals from either 0.75AD or 0.60AD groups did not recover to the lengths of AD group. Plasma concentrations of inorganic P and osteocalcin decreased (P < 0.01) as the level of feed restriction increased. Concentration of plasma bone-specific ALP increased (P < 0.01) by 39.6 and 72.7% in 0.75AD and 0.60AD groups, respectively. After 4 weeks of realimentation, plasma concentrations of osteo­calcin, ALP and P did not differ between all groups. The ulna, humerus and femur linear lengths were directly correlated with the level of osteocalcin and P; however, they showed a negative correlation with the level of ALP. Therefore, plasma concentration of P, osteocalcin and ALP appeared to be suitable bone markers for detecting changes in bone length due to variation in feed restriction levels.

نوع عمل المنشور
بحث علمي
مجلة/صحيفة
Journal of Animal and Feed Sciences,
مزيد من المنشورات
publications

ABSTRACT
We detected genetic variations and single nucleotide polymorphisms (SNPs) of tyrosinase gene (Tyr) among seven camel
populations in Saudi Arabia. Exon 1 of TYR was amplified…

بواسطة Ahmed Hossam Mahmoud
2019