CoO Thin Nanosheets Exhibit Higher Antimicrobial Activity Against Tested Gram-positive Bacteria Than Gram-negative Bacteria.

Journal Article

Musarrat, Shams Tabrez Khan, Rizwan Wahab, Javed Ahmad, Abdulaziz A. Al-Khedhairy, Maqsood A. Siddiqui, Quaiser Saquib, Ali, B.A., and Javed . 2015

• Publication Work Type: Research Article
• Magazine \ Newspaper: Korean Chemical Engineering Research
• Issue Number: 5
• Volume Number: 53
• Pages: 565-569

Publication Abstract

Envisaging the role of Co in theranautics and biomedicine it is immensely important to evaluate its antimicrobial

activity. Hence in this study CoO thin nanosheets (CoO-TNs) were synthesized using wet chemical solution

method at a very low refluxing temperature (90 oC) and short time (60 min). Scanning electron microscopy of the grown

structure revealed microflowers (2~3 μm) composed of thin sheets petals (60~80 nm). The thickness of each individual

grown sheet varies from 10~20 nm. Antimicrobial activities of CoO-TNs against two Gram positive bacteria (Micrococcus

luteus, and Staphylococcus aureus), and two Gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa)

were determined. A 98% and 65% growth inhibition of M. luteus and S. aureus respectively, was observed with 500 μg/ml of

CoO-TNs compared to 39 and 34% growth inhibition of E. coli and P. aeruginosa, respectively with the same concentration

of CoO-TNs. Hence, synthesized CoO-TNs exhibited antimicrobial activity against Gram negative bacteria and

an invariably higher activity against tested Gram positive bacteria. Therefore, synthesized CoO-TNs are less prone to

microbial infections.

Key words: Nanostructures, CoO-TNs, Antibacterial Activity, Theranautics