Identification, Bioactivity, and Productivity of Actinomycins from the Marine-Derived Streptomyces heliomycini

Journal Article

Zhu, Dongyang Wang, Cong Wang, Pengyan Gui, Haishan Liu, Sameh MH Khalaf, Elsayed A Elsayed, Mohammed AM Wadaan, Wael N Hozzein, Weiming . 2017

• Publication Work Type: Research Article
• Magazine \ Newspaper: Frontiers in microbiology
• Volume Number: 8
• Pages: 1147

Publication Abstract

In the process of profiling the secondary metabolites of actinobacteria isolated from the Saudi coastal habitats for production of antibiotics and anti-cancer drugs, the cultures of strain WH1 that was identified as Streptomyces heliomycini exhibited strong antibacterial activity against Staphylococcus aureus. By means of MS and NMR techniques, the active 
compounds were characterized as actinomycins X0β, X2 and D, respectively. The research on the productivity of this strain for actinomycins revealed that the highest production of .