Comparative Histopathological Characterization of Prostate Cancer in Saudi Patients by Conventional and 2005 ISUP Modified Gleason System

Journal Article

E.S, AlSuhaibani, . 2014

• نوع عمل المنشور: ورقة بحثية
• المجلة \ الصحيفة: Asian Pacific Journal of Cancer Prevention
• رقم العدد: 24
• رقم الإصدار السنوي: 15
• الصفحات: 10923-10926

مستخلص المنشور

The aim of this study was to compare the characterization of prostate cancer using the
conventional and 2005 ISUP modified Gleason systems. Materials and Methods: The study employed samples
from 40 prostate cancer patients with resection, biopsy and RP materials. The majority of cases (95%) comprised
adenocarcinoma of the prostate with a modified combined Gleason score of 7 in 20 of the cases (50%). Results:
Upgrading of Gleason scores to a score of 7 occurred in more than 45% of the cases. Conclusion: The study
successfully showed that by the use of the 2005 ISUP modified Gleason system, score 6 cancers decreased from
25% to 17.5% of cases, whereas score 7 cancers increased from 45% to 50%.