publication
Journal Article
2017
View point: Semaphorin-3E: An Emerging Modulator of NK Cells Functions?
, Alamri A. Soussi-Gounni A. kung SK. . 2017
Semaphorin-3E (Sema-3E) is a member of a large family of proteins originally identified as axon guidance cues in neural development. It is expressed in different cell types, such as immune cells, cancer cells, neural cells, and epithelial cells. Subsequently, dys-regulation of Sema-3E expression has been reported in various biological processes that range from cancers to autoimmune and allergic diseases. Recent work in our laboratories revealed a critical immunoregulatory role of Sema-3E in experimental allergic asthma. We further speculate possible immune modulatory function(s) of Sema-3E on natural killer (NK) cells.
Publication Work Type
REVIEW ARTICLE
Volume Number
2337
Issue Number
2337
Magazine \ Newspaper
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Pages
11-18
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