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Dr.Mansour Al Said

Professor

Head of the Medicinal Aromatic Toxic Plants Research Center

كلية الصيدلة
DEP. OF PHARMACOGNOSY COLLEGE OF PHARMACY KING SAUD UNIVERSITY
publication
Conference Paper
1111

Scientific Conferences & Symposiums

1.M.S. Al-Said, W.C. Evans; Alkaloids of the leaves of Erythroxylum hypericifolium, J. Pharm. Pharmacol. Suppl.    (1985).

2. M.S. Al-Said, W.C. Evans and R.J. Grout, Alkoids of the Genus Erythroxylum. Part 5. E. hypericifolium Lam. Root-bark, J.     Chem. Soc. Perkins Trans., 1, 975 (1986).

3. M.S. Al-Said, W.C. Evans and R.J. Grout, Alkaoids of Erythroxylum macrocarpum and E. sideroxyloids, Phytochemistry,       25, 4, 851 (1986).

4.  M.S. Al-Said, W.C. Evans and R.J. Grout; Alkaloids of Erythroxylum hypericifolium stem bark; Phytochemistry, 28, 2,              671‑673 (1989).

5. M.S. Al-Said, W.C. Evans and R.J. Grout; Alkaloids of Erythroxylum hypericifolium leaves; Phytochemistry, 28, 11,       3211‑3215 (1989).

6.  M.S. Al-Said, Pharmacognostical and Biological Studies of Prunus mahaleb L., Proc. Saudi Biol. Soc., 7, 165-173,   Qassim Sym (1984).

7. A.G. Mekkawi, M.S. Al-Said, J.S. Mossa, I.A. Al-Meshal, M.S. Hifnway and M.A. Al-Yahya; Aromatic Plants of Saudi       Arabia, Part II: Essential Oil of Cleome chrysantha, Decne, Proc. Saudi Biol. Soc., 8, 169‑173, Al-Hassa Sym. (1985).

8. M.S. Al-Said, and M.S. Hifnawy; Phytochemical and Biological Screening of Pergularia tomentosa L., Proc. Saudi Biol. Soc. 8, 155‑161 Al‑Hassa Sym. (1985).

9.  A.M. Ageel, N.S. Parmar, J.S. Mossa, M.A. Al-Yahya, M.S. Al-Said, and M. Tariq; Anti-inflammatory Activity of Some Saudi Arabian Medicinal Plants. Agents and Actions, Vol. 17, 383‑384 (1985).

10. M. Tariq, A.M. Ageel, M.A. Al-Yahya, J.S. Mossa, M.S. Al-Said, and N.S. Parmar; Anti-inflammatory Activity of Commiphora molmol, Agents and Actions, Vol. 17, 381‑382 (1985).

11.  M.S. Al-Said, W.C. Evans; Alkaloids of the leaves of Erythroxylum hypericifolum, J. Pharm. Pharmacol. Suppl. (1985).

12.  M.S. Al-Said, W.C. Evans and R.J. Grout, Alkaloids of the Genus Erythroxylum. Part 5. E. hypericifolium Lam. Root-bark, J. Chem. Soc. Perksin Trans. 1, 975 (1986).

13. M.S. Al-Said, W.C. Evans and R.J. Grout, Alkaloids of Erythroxylum macrocarpum and E. sideroxyloides, Phytochemistry, 25, 4, 851 (1986).

14. M.S. Al-Said, A.M. Ageel, N.S. Parmar and M. Tariq; Evaluation of Mastic, a Crude Drug Obtained from Pistacia lentiscus for Gastric and Duodenal Anti-Ulcer Activity. J. of Ethnopharmacology, 15, 271‑278 (1986).
 

15. M.S. Al-Said, and M.S. Hifnawy; Dihydrocoumarins and Certain Other Coumarins from Prunus mahaleb Seeds, J. Nat. Prod., Vol. 49, 4, 721 (1986).

16. M.S. Al-Said, and O.T. Ginawi; Locomotor Activity Studies of Prunus mahaleb in Mice, Fitoterapia, Vol. LVII, 3, 167‑171 (1986).

17. N.S. Parmar, M. Tariq, M.A. Al-Yahya, A.M. Ageel, and M.S. Al-Said; Evaluation of Aloe vera Linn. Leaf Exudate and Gel for Gastric and Duodenal Anti-ulcer Activity, Fitoterapia, LVII, 5, 380-383 (1986).

18. M.S. Al-Said, K.I. Al-Khamis, M.W. Islam, N.S. Parmar, M. Tariq and A.M. Ageel; Post-coital Antifertility Activity of the Seeds of Coriandrum sativum in Rats, Ethnopharmacology, 21,165-173 (1987).

19.  M.S. Al-Said, A.D. Kadertaragan and M.S. Hifnawy; Pharma­cog­nostical and Preliminary Phytochemical Investigation of the Fruit of Pergularia tomentosa L., Int. J. Crude Drug Res., 26, No.1, 9‑16 (1988).

20. M.S. Al-Said, M.S. Hifnawy, A.T. McPhail and D.R. McPhail, Ghala­kinoside, a Cytotoxic Cardiac Glycoside from Pergularia tomentosa, Phytochemistry, 27, 10, 3245-3250 (1988).

21.M.S. Al-Said, E.A. Abdel Sattar, S.l. Khalifa and F.S. EI-Feraly; Isolation and Identification of an Anti-Inflammatory Principle from Capparis spinosa, Pharmazie, 43, 9, 640-641 (1988).

22. K.I. Al-Khamis, M.S. Al-Said, M.W. Islam, M. Tariq, N.S. Parmar and A.M. Ageel; Antifertility, anti-implantation and abortificient activity of the aqueous extract of Cuminum cyminum, Fitoterapia, LIX, 1, 5-9 (1988).

23.  M.S. Al-Said, J.S. Mossa and M.M. Al-Azizi; Chemical Investigation of Salsola imbricata Forssk, Proc. Saudi BioI. Soc., 11, 195-199 (1988).

24. M.S. Al-Said, W.C. Evans and R.J. Grout, Alkaloids of Erythroxylum hypericifolium leaves; Phytochemistry, 28, 11, 3211-3215 (1989).

25. M.S. Al-Said, W.C. Evans and R.J. Grout, Alkaloids of Erythroxylum hypericifolium stem bark; Phytochemistry, 28, 2, 671-673 (1989).

26.  M.S. Al-Said, S.I. Khalifa and F.S. EI-Feraly, 4, 13-a-Epoxymuzigadia, A sesquiterpene from Canella winterana, Phytochemistry, 28, 1, 297­ 198 (1989).

27. M.S. Al-Said, S.I. Khalifa, F.S. EI-Feraly and C.D. Hufford; Biogenetic­-Type Synthesis of Vulgarian and Peroxyvulgarian, Phytochemistry, 28, 1, 107-108 (1989).

28.  M.S. Al-Said, A.A. Jayab and M.S. Hifnawy; Biochemical Studies on Ghalakinoside, a Possible Antitumor Agent from Purgularia tomentosa, Ethnopharmacology, 27235-240 (1989).
 

29.  N.S. Pannar, J.S. Mossa, M.A. Al-Yahya, M.S. Al-Said, M. Tariq and A.M. Ageel; Anti-inflammatory and antipyretic Activity of Euphorbia peplis L., Int. J. Crude Drug Res., 27, 1, 9-13 (1989).

30. M. Tariq, A.M. Ageel, M.A. Al-Yahya, J.S. Mossa, and M.S. Al-Said; Anti-inflammatory activity of Teucrium polium, Int. J. Tiss. Reac. XI, 4, 185-188 (1989).

31. A.M. Ageel, J.S. Mossa, M.A. Al- Yahya, M.S. Al-Said and M. Tariq; Experimental Studies on Antirheumatic Crude Drugs Used in Saudi Traditional Medicine, Drugs Exptl. Clin. Res. XV, 8, 369-372 (1989).

32. M.S. Al-Said, S.M. EI-Khawaja, F.S. EI-Feraly and C.D. Hufford; 9‑Deoxy Drimane Sesquiterpenesa from Canella winterana, Phytochemistry, 29, 3, 975-977 (1990).

33. M.S. Al-Said, M.Tariq, M.A. Al-Yahya, S. Rafatullah, G.T. Ginnawi and A.M. Ageel; Studies on Ruta Chalepensis, An Ancient Medicinal Herb Still Used in Traditional Medicine; Ethnophannacology, 28, 305‑312 (1990).

34. M.A. Al-Yahya, S. Rafatullah, J.S. Mossa, A.M. Ageel, M.S. Al-Said and M. Tariq; Gastric Anti secretory, Antiulcer and Cytoprotective Properties of Ethanolic Extract of Alpinia galanga willd in Rats, Phytotherapy Research, 4, No.3, 112-114 (1990).

35.  A.T. McPhail, D.R. McPhail, M.S. Al-Said, M.M. EI-Domiaty and F.S. EI-Feraly; Revision of the stereochemistry of (+)- Tuberine, An Alkaloid from Haplophyllum tuberculatum, Phytochemistry, 29, 9, 3055-3057 (1990).

36.  M.S. Hifnawy, M.S. Al-Said and S.S. Al-Hawary, Pergularotoside, a new cardiac glycoside from Pergularia tomentosa L., Al-Azhar J. of Natural Products, Vol. 5, 186-197 (1990).

37. M.A. Al-Yahya, M.M. EI-Domiaty, LA. Al-Meshal, M.S. Al-Said and F.S. EI-Feraly; (+)-Dihydroperfamine: an Alkaloid from Haplophyllum tuberculatum; Int. J. Phannacoanosy, 29, No.4, 268- 272 (1991).

38. M.S. Al-Said, A.S. Khalifa and M.M. Al-Azizi, Flavonoids from Cissus digitata; Int. J. Pharmacognosy, 29, No.4. 281-283 (1991).

39. J.S. Mossa, M. Tariq, A. Mohsin, A.M. Ageel, M.A. Al-Yahya, M.S. Al‑Said and S. Rafatullah; Pharmacological Studies on Aerial Parts of Calotropis procera; American Journal of Ch. Medicine, Vol. XIX, Nos. 3-4, 223-231 (1991).

40. M. W. Islam, M. Tariq, A.M. Ageel, M.S. Al-Said and M.A. Al-Yahya, Effect of Saliva haematodes on Sexual behaviour of male Rats, Ethnopharmacology, 33, 67-72 (1991).

41. S. Rafatullah, J.S. Mossa, M. Tariq, M.S. Al-Said, A.M. Ageel and M.A. Al-Yahya; Ethnopharmacology of Lepidum sativum seeds, J. Ethnopharmacology, 1991 (communicated).

42.  M.M. Al-Harbi, M.S. Al-Said and M.M. Al-Azizi, Preliminary Phytochemical and Pharmacological Studies on Anisotes trisulcus, Pharmacognosy, 30, No.2, 87-92 (1992).

43.  M.A. Al-Yahya, A.J. Al-Rehaily, M.S. Ahmad, M.S. Al-Said and F.S. EI-Feraly, New Alkaloids from Haplophyllum tuberculatum, Journal of Natural Products, 55, 7, 899-903 (1992).

44.  M.S. Al-Said, Traditional Medicinal Plants of Saudi Arabia, American Journal of Ch. Medicine, Vol. XXI, No.3-4, 291-298 (1993).

45. M.S. Al-Said, M.M. Al-Azizi, A.M. Galal, J.S. Mossa and M.M. El‑Olemy; GC/MS Analysis of Volatile Oil of Salsola imbricata forssk, Az. I. Pharm. Sci. Vol 11, (1993).

46. S. Rafatullah, M. Tariq, J.S. Mossa, M.A. Al-Yahya, M.S. Al-Said, and A.M. Ageel; Protective effect of Swerita chirata against Indomethacin and other ulcerogenic agent-induced gastric ulcers; Drug Exptl. Clin. Res XIX (2), 69-73 (1993).

47.  S. Rafatullah, M.A. Al-Yahya, M.S. Al-Said, K.U. Abdulhameed and J.S. Moosa; Gastric Anti-ulcer and Cytoprotective Effects of 'Guar' Cyamopsis tetragonoloba (L.) Taub. in Rats, Int. I. of Pharmacognosy, 132, No.2, 163-170 (1994).

48. M.M. El-Olemy, H. Elhag, M. El-Domiaty, E. Abdel Sattar, M.M. Al­Azizi and M.S. Al-Said; Biotransformation of Digitoxigenin by Cell Suspension Cultures of Pergularia tomentosa and Ammi visnaga, Saudi Pharm. Journal, No.2, Vol. 2, (1994).

49. M.M. Al-Azizi, M.S. Al-Said, M.M. El-Olemy, E.A. Sattar and A.S. Khalifa; Rhombifoline and 5,6-Dehydrolupanine from Anagyrus foetida L., Archieves of Pharm. Research, Vol. 17, No.6, 393-397 (1994).

50. S. Rafatullah, M. Tariq, J.S. Mossa, M.A. Al-Yahya, M.S. Al-Said and A.M. Ageel; Antisecretagogue, anti-ulcer and cytoprotective properties of Acorus calamus in rats, Fitoterapia, Vol. LXV, No.1, 19-23 (1994).

51.  S. Rafatullah, A.M. Galal, M.A. Al-Yahya and M.S. Al-Said; Gastric and Duodenal Antiulcer and Cytoprotective Effects of Aframomum melegueta in Rats; Int. J. Pharmacognosy, Vol. 33, No.4, 311-316 (1995).

52. M.S. Al-Said, E.A. Sattar, F.S. EI-Feraly, A. Nahrstredt and M. Coen; New Sulfides from Ferula rutabensis, Int. J. Pharmacognosy, Vol. 34, No.3, 189-193 (1996).

53.  A.S. Ibrahim, F.S. El-Feraly and M.S. Al-Said; Microbiological Transformation of Dic1ofenac, Saudi Pharm. J. Vol. 4, No. 3-4, 165-169, July-Oct. (1996).
 

54.  M.S. Al-Said, K.A. Al-Rashood, K.I. Al-Khamis, M.I Al-Yamani, S.A. Al-Bella, T.A. Al-Najjar, S.M. Alam and R. Dham; Bioequivalence Evaluation of 500 mg Amoxicillin Capsules in Healthy Human Volunteers -Single Dose under fasting Conditions, JAMA, Middle East, 73-77 (1999).

55.  K.Y. Orabi, K.A. EI-Sayed, M.S. Al-Said, and F.S. Elferaly; Sesquiterpene Lactones from Onopordum ambigum, Saudi Pharm. Journal, Vol. 8, No. 2-3 (2000).

56.  I. Muhammad, K.A. El-Sayed, J.S. Mossa, M.S. Al-Said, F.S. El-Feraly, A.M. Clark, CD. Hufford, S. Ohand and A.M. Mayer; Bioactive 12, Oleanene Triterpene and Secotriterpene Acids from Maytenus undata, J. Nat. Prod., 63, 605-610 (2000).

57.  A.J.AL-Rehaily, M.S.Al-Said, M.A.AL-Yahya, J.S.Mossa and S.Rafatullah, Ethnopharmacological studies on Allspice (Pimenta dioica) in Lab Animals, Pharmaceutical Biology, 40(3), 200-205(2000).

58.  K. EI-Sayed, M.S. Al-Said, F.S. El-Feraly, and S.A. Ross; New Quinoline Alkaloids from Ruta Chalepensis; Vol. 63, No.7, 995-997 (2000).

59.  A.A. Gohar, M.M. El-Olemy, E.A.. Sattar, M.S. Al-Said and M. Niwa; Cardenolides and b-sitosterol Glucoside from Pergularia tomentosa L., Natural Prod. Sciences 6(3), 142-146 (2000).

60. Mansour S. Al-Said, Khalil I. Al-Khamis, Esmail M. Niazy, Yousry M. El‑Sayed, Khalid A. Al-Rashood, Sulaiman, Al-Bella, Mohd A. Al‑Yamani, Tawfeeq A. Al-Najjar, Syed M. Alam, Ruwayda Dham, Zaman Q. Qumaruzaman. Bioequivalence evaluation of two brands of cefuroxime 500 mg tablets (Cefuzime and Zinnat) in healthy human volunteers.  Bipharmaceutics and Drug Disposition, 21(6), 205‑210 (2000).

61. A.M. Galal, B.A. Abourashed, S.A. Ross, M.A. ElSohly, M.S. Al-Said and F.S. EI-Feraly; Ducan Sesquiterpenes from Ferula hermonis; J. Nat. Prod., Vol. 64, No.3, 399-400 (2001).

62. M. Atiqur Rahman, Mansour S. Al-Said, Jaber S. Mossa, Mohammed A. Al-Yahya and M.A. Fahd Al-Hemaid; A Check List of Angiosperm Flora of Farasan Islands, Kingdom of Saudi Arabia, Pakistan Journal of Biological Sciences 5(11): 1162‑1166 (2002).

63.  K.Y. Orabi, K.A. El-Sayed, M.T. Hamann, D.C. Dunbar, M.S. Al-Said, T. Hega and M. Kelly; Araguspongines K and L, New Bioactive Bis‑1-Ovaquinolizidine N‑Oxide Alkaloids from Res Sea Specimens of Xestospongia exigua, J. Nat. Prod., 65, 1782‑1785 (2002).

64. A.J. Al-Rehaily, K.A. El‑Sayed, M.S. Al-Said and B. Ahmed; Trisulcusine: A Novel Spiro Quinazoline Alkaloid from Anisotes trisulcus, Ind. J. Chem., Vol. 41B, 2385‑2389 (2002).

65. H. Elhag, M.M. El-Olemy and M.S. Al-Said; Enhancement of Somatic Embryogenesis and Production of Developmentally Arrested Embryos in Nigella sativa. HortScience, Vol.39 No 2 (2004).
 

66. B. Ahmed; T.A.AL-Howiriny; J.S.Mossa; and M.S. Al-Said; Three new and two rare furanoeremophilanes from Senecio asirensis; Journal of Asian Prod. Res. 6(3), 167-175 (2004).

67.  I.A.AL-Sarra; M.S. Al-Said; K.I.AL-Khamis; E.M.Niazy; Y.M.EL-Sayed; K.A.AL-Rashood; M.J.AL-Yamani; and S.A.AL-Balla. Comparative bioavailability of doxycycline hyclate (equivalent to 100 mg doxycycline) capsules (doxyuin vs. vibramycin) for bioequivalence evaluation in healthy adult volunteers. Int. J. of clinical pharmacology and Therapeutics; vol. 42-No. 7/2004 (373-377).

68. T.A.AL-Howiriny; M.O. AL-Sohaibani; M.S. Al-Said; M.A.AL-Yahya; K.H.EL-Tahir; S. Rafatullah; Hepatoprotective properties of Balessan "Commiphora opobalsamum": A Traditional Medicinal plant of Saudi Arabia. Drugs under Experimental and Clinical Research. XXX (5/6) 213-220 (2004).

69. T.A.AL-Howiriny; M.A.AL-Yahya; M.S. Al-Said; K.H.EL-Tahir; and S.Rafatullah. Studies on the pharmacological activities of an Ethanol extract of Balessan "Commiphora opobalsamum".  Pakistan J. of Biol. Sciences, 7 (11): 1933-1936, 2004.

70.  M.A.AL-Karawi, A.S.AL-Blowi, M.S. Al-Said, Y.B.AL-Rweli, Herbal-induced dysphagia by granules containing Starch and Morphine. The Saudi Journal of Gastroenterology, Vol.10, No.1, pp32-33, Dhul Quada 1424 H, Jan. 2004.

71. M.A.Rahman, J.S.Mossa, M.S. Al-Said, and M.A.AL-Yahya, Medicinal plant Diversity in The Flora of Saudi Arabia 1: A Report on Seven plant Families. Fitoterapia, 75, 149-161, 2004.

72. T.A.AL-Howiriny, M.O. AL-Sohaibani; M.S. Al-Said; M.A.AL-Yahya;  K.H.EL-Tahir; S.Rafatullah, Effect of Commiphora opobalsamum (L) Engl. (Balessan) on Experimental gastric ulcers and secretion in rats. J. Ethnopharmacology, 98, 287-294 (2005).

73.  Y.A.Asiri, M.S. Al-Said, K.I.AL-Khamis, E.M.Niazy, Y.M.EL-Sayed, K.A.AL-Rashood, M.J.AL-Yamani, I.A.AL-Sarra and S.A.AL-Balla, Comparative bioavailability study of cefixime (equivalent to 100 mg/5ml) suspension (Winex vs Suprax) in healthy male volunteers. Int. J. of Clinical and Therapeutics, Vol. 43-No.10, 499-504, 2005.

74. M.S. Al-Said, M. Ghorab, S. Alqasoumi, E. El-Hossary, E. Noaman, Synthesis and in vitro anticancer screening of some novel 4-[2-amino-3-cyano-4-substituted-5,6,7,8-tetrahydro-quinoline-1-(4H)-yl]benzene­sulfonamides. European J. of Med. Chem., 45, 3011-3018 (2010).

75.  M.S. Al-Said, M.M. Ghorab, M.S. Al-Dosari, M.M. Hamed. Synthesis and in vitro anticancer evaluation of some novel hexahydroquinoline derivatives having a benzenesulfonamide moiety. Eur. J. Med. Chem., 46(1), 201-207 (2011).

76.  M.S. Al-Said, M.S. Bashandy, S.I. Alqasoumi, M.M. Ghorab. Anti-breast cancer activity of some novel 1,2-dihydropyridine, thiophene and thiazole derivatives. Eur. J. Med. Chem., 46(1), 137-141 (2011).

77.  M.S. Al-Said, M.S. Bashandy, M.M. Ghorab. Novel quinolones bearing a biologically active trimethoxyphenyl moiety as a new class of antitumor agents, Arzneimittel-Forschung-Drug Research, 61(9), 527-531 (2011).

78. M.S. Al-Said, A.I. Alqsoumi, M.M. Ghorab. Design and synthesis of some novel hydrazide, 1,2-dihydropyridine, chromene derivatives carrying biologically active sulfone moiety with potential anticancer activity, Arzneimittel-Forschung-Drug Research, 61(9) 521-526 (2011).

79. M.M. Ghorab, M.S. Al-Said, E.M. El-Hossary. In vitro cytotoxic evaluation of some new heterocyclic sulfonamide derivatives. J. Heterocyclic. Chem, 48(3), 563-571 (2011).

80.  A.J. Al-Rehaily, M.S. Al‑Said and K.E.H. El Tahir. Peganine isolated from Anisotes trisulcus as a smoking deterrent and anorexigenic agent. African Journal of Pharmacy and Pharmacology, 5(11), 1342-1348 (2011).

81. Mansour S. Al-Said, Ramzi A. Mothana, Mohammed O. Al-Sohaibani and Syed Rafatullah. Ameliorative effect of Grewis tenax (Forssk) Fiori Fruit Extract on CCl4-induced oxidative stress and hepatotoxicity in rats. Journal of Food Science 76(9) (2011).

82. Ramzi A. Mothana, Mansour S. Alsaid and Nawal M. Al‑Musayeib. Phytochemical analysis and in vitro antimicrobial and free-radical-scavenging activities of the essential oils from Euryops arabicus and Laggera decurrens. Molecules 16, 5149-5158 (2011).

83.  M.S. Al-Said, Ghorab, M.M., Nissan, Y.M. Dapson in heterocyclic chemistry, Part VIII: Synthesis, molecular docking and anticancer activity of some novel sulfonylbiscompounds carrying biologically active 1,3‑dihydropyridine, chromene and chromenopyridine moieties. Chem. Cent. J., 6(1), 64 (2012).

84.  M.M. Ghorab, M.S. Al‑Said, Y.M. Nissan. Dapson in heterocyclic chemistry Part VI: Synthesis and molecular docking of some novel sulfone biscompounds of expected anticancer activity, Arzneimittelforschung, Sept 21 (2012). DOI: 10.1055/S-0032-1323660.

85. M.M. Ghorab, M.S. Al-Said, Y.M. Nissan. Dapson in heterocyclic chemistry, Part V: Synthesis, molecular docking and anticancer activity of some novel sulfonylbiscompounds carrying biologically active dihydropyridine, dihydroisoquinoline, 1,3-dithiolan, 1,3-dithian, acrylamide, pyrazole, pyrazolopyrimidine and benzochromene moieties. Chem. Pharm. Bull, 60(8), 1019-2028 (2012).

86. M.M. Ghorab, M.S. Al-Said. Antitumor activity of novel pyridine, thiophene and thiazole derivatives. Arch. Pharm. Res. 35(6), 965-973 (2012).

87.  M.M. Ghorab, M.S. Al-Said. Anticancer activity of novel indenopyridine derivatives. Arch. Pharm. Res., 35(6), 987-994 (2012).

88.  M.S. Al-Said, M.G. Al-Gazzar, M.S. Al-Dosari, M.M. Ghorab. Synthesis, anticancer activity and radiosensitizing evaluation of some new 2‑pyridone derivatives, Arznemittelforschung- Drug Res., 62(3), 149-156 (2012).

89.  M.S. Al-Said, M.G. Al-Gazzar, M.M. Ghorab. In-vitro cytotoxic and radiosensitizing evaluation of novel 2‑pyridine, isoquinoline, chromene and chromenopyridone derivatives. Eur. J. Chem., 3(2), 228-234 (2012).

90. M.M. Ghorab, M.S. Al-Said. Synthesis and antitumor activity of some novel hydrazide, 1,2‑dihydropyridine, chromene, and benzochromene derivatives. J. Heterocyclic Chem., 49(2), 272-280 (2012).

91. M.S. Al-Said, M.M. Ghorab, H.A. Ghabbour, S. Arshad, H.K. Fun. 1‑(3‑Ethylphenyl)-4,6‑dimethyl-2-oxo-1,2-dihydropyridine-3-carbo­nitrile. Acta Cryst. E68, 01679 (2012).

92.  M.M. Ghorab, M.S. Al-Said, M.S. Abdel-Kader, M. Hemamalini, H.K. Fun. Absolute configuration of (1S,2S)-3-methyl-2-phenyl-2,3-dihydrothiazolo[1,3‑b]quinazolin-5-one, Acta Cryst. E68, 0928 (2012).

93. M.S. Al‑Said, M.M. Ghorab, H.A. Gabbour, C.K. Quah, H.K. Fun. 4‑[(5,5‑Dimethyl-3-oxocyclohex-1-enyl)-amino]benzenesulfonamide, Acta Cryst. E68, 02370 (2012).

94. M.M. Ghorab, M.S. Al-Said, H.A. Ghabbour, S. Chantrapromma, H.K. Fun. (E)‑4-Amino-N-(1,2-dihydropyridine-2-ylidene)­benzene­sulfona­mide nitromethane monosolvate. Acta Cryst. E68, 01030 (2012).

95. M.S. Al-Said, M.M. Ghorab, S. Chantrapromma, H.K. Fun. (3Z,3Z)-3,3‑(3,5-Dimethylfuran-2,4-diyl)bis(4‑hydroxypent-3-en-2-one). Acta Cryst., E68, 0847-0848 (2012).

96.  M.S. Al-Said, H.A. Ghabbour, T.S. Chia, H.K. Fun. Ethyl 2‑amino-4,5-dimethylthiophene-3-carboxylate, Acta Cryst. E68, 02111 (2012).

97.  M.M. Ghorab, M.S. Al‑Said, A.A. Al‑Mishari, C.K. Quah, H.K. Fun. 4‑[(7‑Trifluorometyyl)quinolin-4-yl]amino]benzenesulfonamide- ethanol- methanol (1/0.47/0.53), Acta Cryst. E68, 02396 (2012).

98. M.M. Ghorab, M.S. Al‑Said, H.A. Ghabbour, T.S. Chia, H.K. Fun. (E)‑3‑Dimethylamino-1-(2,5‑dimethylthiophene-3-yl)prop-2-en-1-one, Acta Cryst. E68, 01712-01713 (2012).

99.  M.M. Ghorab, M.S. Al-Said, S.I. Alqasoumi, T.S. Chia, H.K. Fun. 3‑[(1-Hydroxy-1-phenylpropan-2-yl)amino]-5,5-dimethylcyclohex-2-enone, Acta Cryst. E68, 01436-01437 (2012).

100. Ramzi A.A. Mothana, Mansour S. Al‑Said, Adnan J. Al‑Rehaily, Tunis M. Thabet, Nasser a. Awad, Michael Lalk, Ulrike Lindequist. Anti-inflammatory, antinociceptive, antipyretic and antioxidant activities and peholic constituents from Loranthus regularis Steud. Ex Sprague. Food Chemistry 130, 344-348 (2012).

101. Mansour S. Al‑Said, Ramzi A. Mothana, Mohammed A. Al‑Yahya, Ali S. Al-Blowi, Mohammed Al‑Sohaibani, Atallah F. Ahmed, and Syed Rafatullah. Edible oils for liver protection: Hepatoprotective potentiality of Moringa oleifera seed oil against chemical-induced hepatitis in rats. Journal of Food Science 77(7), T124 (2012).

102.    Ramzi A. Mothana, Mansour S. Alsaid, Sidgi S. Hasoon, Nawal M. Al-Mosaiyb, Adnan J. Al-Rehaily, and Mohamed    A. Al-Yahya.  Antimicrobial and antioxidant activities and gas chromatography mass spectrometry (GC/MS) analysis of the essential oils of Ajuga bracteosa Wall. ex Benth. and Lavandula dentata L. growing wild in Yemen.  Journal of Medicinal Plants Research, 6(15): 3066-3071 (2012).

103. M.S. Al-Dosari, M.M. Ghorab, M.S. Al-Said, Y.M. Nissan. Discovering some novel-7-chloroquinolines carrying a biologically active benzenesulfonamide moiety as a new class of anticancer agents. Chem. Pharm. Bull, 61(1) 50-58 (2013).

104.  Mohammed Al-Yahya, Ramzi Mothana, Mansour Al-Said, Mohammed Al-Dosari, Nawal Al-Musayeib, Mohammed Al-Sohaibani, Mohammad Khalid Parvez, and Syed Rafatullah. Attenuation of CCl4-induced oxidative stress and hepatonephrotoxicity by Saudi sidr honey in rats. Evidence-Based Complementary and Alternative Medicine, Volume 2013, Article ID 569037 (2013).

105. Mohammed A. Al-Yahya, Ramzi A. Mothana, Mansour S. Al-Said, Kamal Eldin El-Tahir, Mohammed Al-Sohaibani and Syed Rafatullah. Citrus medica “Otroj”:  Attenuates oxidative stress and cardiac dysrhythmia in isoproterenol-induced cardiomyopathy in rats. Nutrients 5(11), 4269-4283 (2013). doi: 10.3390/nu5114269.

106. Ramzi Mothana, Mansour S. Alsaid, M. Al-Yahya, Adnan J. Al-Rehaily and Jamal M. Khalid. GC and GC/MS of essential oil composition of the endemic sogotraen Leucas virgata and its antimicrobial and antioxidant activities. Int. J. Mol. Sci. 14, 23129-23139 (2013).

107. Mostafa Ghorab, Mansour Alsaid and Yassin Nissan. Anti-breast cancer of some novel pyrrole and pyrollopyrimidine derivatives bearing a biological active sulfonamide moiety. Life Science Journal, 10(4) (2013).

108. M. Ghorab, A. Al-Dhfyan, M. El-Gazzar, M. Alsaid. Antiproliferative activity of novel thiophene and thienopyrimidine derivatives. Drug Res. 08-0394 (2013).

109. M.S. Alsaid, M.G. El-Gazear, M.M. Ghorab. Anticancer activity of novel thiophenes containing a biological active diphenylsulphone, diazepin, piperidine, oxazepine, acryladehyde and sulphonamide moieties. Drug Res. 63; 1-7 (2013).

110. Mahmoud Bashandy, Mansour Alsaid, Reem Arafa and Mostafa Ghorab. Design, synthesis and molecular docking of novel N,N‑di­methylbenzenesulfonamide derivatives as potential antiproliferative agents. J. Enzyme Inhib. Med. Chem. Early online 1-9 (2013).

111.Mohammed Al-Dosari, Mostafa Ghorab, Mansour Alsaid, Yassin Nissan, Abdulkareem Ahmed. Synthesis and anticancer activity of some novel trifluoromethylquinolines carrying a biologically active benzenesulfonamide moiety. Europ. J. of Med. Chem. 69, 373-383 (2013).
 

112.  Victor Kuete, Benjamin Wiench, Mansour S. Alsaid, Muhammad A. Alyahya, Aimé G. Fankam, Abdelaaty A. Shahat and Thomas Efferth. Cytotoxicity, mode of action and antibacterial activities of selected Saudi Arabian medicinal plants. BMC Complementary and Alternative Medicine, 13, 354 (2013).

113.  Ibrahim Al-Mofleh, Mohamed Al-Sobaihani, Saleh Alqasoumi, Mansour Al-Said, Mohammed Al-Dosari, Mohammed Al-Yahya, Syed Rafatullah. Fennel "Foeniculum vulgare" treatment protects the gastric mucosa of rats against chemically-induced histological lesions. International Journal of Pharmacology, 9(3), 182-189 (2013).

114.   Mansour AlSaid, Ibrahim Al-Mofleh, Mohammad Raish, Mohammed Al-Sobaihani, Mohammed Al-Yahya and Syed Rafatullah. Antiulcerogenic, anti-secretory and cytoprotective effects of Piper cubeba (L.) on experimental ulcer models in rat. International Journal of Biotechnology for Wellness Industries, 2, 173-182 (2013).

115.  Abdelaaty A. Shahat, Mansour S. Alsaid, Muhammad A. Alyahya, Maureen Higgins, Albena T. Dinkova-Kostova. NAD(P)H: Quinone oxidoreductase 1 inducer activity of some Saudi Arabian medicinal plants. Planta Medica, 79, 459-464 (2013).

116.  Mostafa Ghorab, Maureen Higgins, Mansour Alsaid, Reem Arafa, Abdelaaty Shahat, Albena Dinkova-Kostova. Synthesis, molecular modeling and NAD(P)H: quinone oxidoreductase 1 inducer activity of novel cyanoenone and enone benzensulfonamides. J. Enzyme Inhib. Med. Chem. Early Online: 1-6 (2014).

117.   Mostafa Ghorab, Marwa El-Gazzar and Mansour Alsaid. Synthesis and anti-breast cancer evaluation of novel N-(guanidinyl) benzenesulfonamides. Int. J. Mol. Sci. 15, 5582-5595 (2014).

118.  Mostafa Ghorab, Maureen Higgins, Mansour Alsaid, Reem Arafa, Abdelaaty Shahat, Albena Dinkova-Kostova. Synthesis, molecular modeling and NAD(P)H: quinone oxidoreductase 1 inducer activity of novel cyanoenone and enone benzensulfonamides. J Enzyme Inhib Med Chem, 29, 840–845 (2014).

119.  Mostafa Ghorab, Marwa El-Gazzar and Mansour Alsaid. Synthesis and anti-breast cancer evaluation of novel N-(guanidinyl) benzenesulfonamides. Int. J. Mol. Sci. 15, 5582-5595 (2014).

120.   Awwad A. Radwan, Mostafa M. Ghorab, Mansour S. Alsaid, Fares K. Alanazi.  Novel ethyl 1,5-disubstituted-1H-pyrazole-3-carboxylates as a new class of antimicrobial agents.  Acta Pharm. 64, 335–344 (2014).

121. Mostafa M. Ghorab, Marwa G. El-Gazzar and Mansour S. Alsaid.  Design and synthesis of novel thiophenes bearing biologically active aniline, aminopyridine, benzylamine, nicotinamide, pyrimidine and triazolopyrimidine moieties searching for cytotoxic agents.   Acta Poloniae Pharmaceutica – Drug Research, 71, 401‑407 (2014).

122.  Mostafa M. Ghorab, Mahmoud S. Bashandy, Mansour S. Alsaid.  Novel thiophene derivatives with sulfonamide, isoxazole, benzothiazole, quinoline and anthracene moieties as potential anticancer agents.  Acta Pharm., 64, 419–431 (2014).

123.  Mostafa M. Ghorab, Mansour S. Alsaid and Yassin M. Nissan.  Synthesis and molecular docking of some novel anticancer sulfonamides carrying a biologically active pyrrole and pyrrolopyrimidine moieties.  Acta Poloniae Pharmaceutica – Drug Research, 71, 603‑614 (2014). 

124. Mostafa M. Ghorab, Mansour S. Alsaid, Hazem A. Ghabbour and Hoong-Kun Fun.   Design, synthesis, x-ray crystallographic study and anticancer activity of novel 4-(7-chloro-1-methylquinolin-4-(1H)-ylideneamino)-phenyl-3-(dimethylamino)-prop-2-en-1-one.  Asian Journal of Chemistry; 26, 8497-8500 (2014).

125. Mostafa M. Ghorab, Maureen Higgins, Albena T. Dinkova-Kostova, Mansour S. Alsaid, and Abdelaaty A. Shahat.  Novel thioureido derivatives carrying thione and sulfonamide moieties induce the cytoprotective enzyme nad(p)h:quinone oxidoreductase 1.  Asian Journal of Chemistry, 26, 8501-8504 (2014).

126.  Abdelaaty A. Shahae, Abeer Y. Ibrahim, Mansour S. Elsaid.  Polyphenolic content and antioxidant activity of some wild Saudi Arabian asteraceae plants.  Asian Pacific Journal of Tropical Medicine, 545-551 (2014). doi: 10.1016/S1995-7645(14)60091-2

127. Ali A. El Gamal, Mansour S. AlSaid, Mohammad Raish, Mohammed Al-Sohaibani, ShazaM. Al-Massarani, Ajaz Ahmad, Mohamed Hefnawy, Mohammed Al-Yahya, Omer A. Basoudan, and Syed Rafatullah.  Beetroot (Beta vulgaris l.) extract ameliorates gentamicin-induced nephrotoxicity associated oxidative stress, inflammation, and apoptosis in rodent model.  Mediators of Inflammation, Volume 2014, Article ID 983952, 12 pages.  http://dx.doi.org/10.1155/2014/983952

128.  Mostafa M. Ghorab, Mansour S. Alsaid, Mariangela Ceruso, Yassin M. Nissan, Claudiu T. Supuran.  Carbonic anhydrase inhibitors: Synthesis, molecular docking, cytotoxic and inhibition of the human carbonic anhydrase isoforms I, II, IX, XII with novel benzenesulfonamides incorporating pyrrole, pyrrolopyrimidine and fused pyrrolopyrimidine moieties.  Bioorganic & Medicinal Chemistry, 22, 3684–3695 (2014).

129. Mostafa M. Ghorab, Saleh I. Alqasoumi, Maged S. Abdel-Kader and Mansour S. Alsaid.  Utility of l-norephedrine in the semisynthesis of novel Thiourea and thiazolidine derivatives as a new class of anticancer agents.  Acta Poloniae Pharmaceutica – Drug Research, 71, 615–623 (2014).

130. Mostafa M. Ghorab, Marwa G. El-Gazzar and Mansour S. Alsaid.  Synthesis, characterization and anti-breast cancer activity of new 4-aminoantipyrine-based heterocycles.  Int. J. Mol. Sci., 15, 7539-7553 (2014). doi:10.3390/ijms15057539.

131. Adnan Jathlan Al-Rehaily, Mohammad Shamim Ahmad, Muhammad Yousaf, Shabana Iqrar Khan, Jamal Mustafa, Babu Lal Tekwani, Melissa Jacob, Mohammed Abdulaziz Al-Yahya, Mansour Sulaiman Al‑Said, Jianping Zhao, Ikhlas Ahmad Khan.  Bioactive Chemical Constituents of Ononis natrix.  J. Chem. Soc. Pak., 36, 1114-1121 (2014).

132. Ramzi A. Mothana, Mansour S. Al-Said, Nawal M. Al-Musayeib, Ali A. El Gamal, Shaza M. Al-Massarani, Adnan J. Al-Rehaily, Majed Abdulkader and Louis Maes.  In vitro antiprotozoal activity of abietane diterpenoids isolated from Plectranthus barbatus Andr.  Int. J. Mol. Sci., 15, 8360-8371 (2014).

133. Mostafa M. Ghorab, Mariangela Ceruso, Mansour S. Alsaid, Yassin M. Nissan, Reem K. Arafa, Claudiu T. Supuran.  Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling.  European Journal of Medicinal Chemistry, 87, 186e196 ((2014).

134. Abdelaaty A. Shahat, Abeer Y. Ibrahim, Essam Ezzeldin, and Mansour S. Alsaid.   Acetylcholinesterase inhibition and antioxidant activity of some medicinal plants for treating neuro degenarative disease.   Afr J Tradit Complement Altern Med. 12, 97-103 (2015).

135. Muhammad Yousaf, Adnan J. Al-Rehaily, Mohammad S. Ahmad, Jamal Mustafa, Mohammed A. Al-Yahya, Mansour S. Al-Said, Jianping Zhao, Ikhlas A. Khan. A 5-alkylresorcinol and three 3,4-dihydroisocoumarins derived from Ononis natrix. Phytochemistry Letters 13, 1-5 (2015)

136. Ahmed H. Arbab, Mohammad K. Parvez, Mohammed S. Al-Dosari, Adnan J. Al-Rehaily, Mohammed Al-Sohaibani, Elwaleed E. Zaroug, Mansour S. AlSaid, and Syed Rafatullah.  Hepatoprotective and antiviral efficacy of Acacia mellifera leaves fractions against Hepatitis B virus.  BioMed Research International, Volume 2015, Article ID 929131, 10 pages.  http://dx.doi.org/10.1155/2015/929131

137. Mostafa M. Ghorab, Mansour S. Alsaid and Yassin M. Nissan.  Novel pyrrolopyrimidines and triazolopyrrolopyrimidines carrying a biologically active sulfonamide moieties as anticancer agents.  Acta Poloniae Pharmaceutica – Drug Research, 72, 65-78 (2015).

138.  Mostafa M. Ghorab, Mansour S. Alsaid, Abdullah-Al-Dhfyan and Reem K. Arafa.  Cytotoxic activity of some novel sulfonamide derivatives.  Acta Poloniae Pharmaceutica – Drug Research, 72, 79‑87 (2015).

139.  Mostafa M. Ghorab, Mansour S. Alsaid.  Novel 4-aminoquinazoline derivatives as new leads for anticancer drug discovery.  Acta Pharm. 65, 299–309 (2015).

140.  Mostafa M. Ghorab, Mansour S. Alsaid.  Anti-breast cancer activity of some novel quinoline derivatives.  Acta Pharm., 65, 271–283 (2015).

141. Abdelaaty A. Shahat, Mansour S Alsaid, Soheir E. Kotob, Hanaa H. Ahmed.  Significance of Rumex vesicarius as anticancer remedy against hepatocellular carcinoma: A proposal-based on experimental animal studies.  Asian Pac J Cancer Prev, 16, 4303-4310 (2015).

142.  Mostafa M. Ghorab, Mansour S. Alsaid.  Synthesis of some tricyclic indeno [1, 2-d] pyrimidine derivatives as a new class of anti-breast cancer agents.  Biomedical Research, 26, 420-425 (2015).

143.  Mansour S. Alsaid, Mostafa M. Ghorab, Maureen Higgins, Albena T. Dinkova-Kostova, Abdelaaty A. Shahat.  NAD(P)H: Quinone oxidoreductase 1 inducer activity of some enaminone derivatives.  Biomedical Research, 26, 7-12 (2015).

144. Atallah F. Ahmed, Jawaher H. Al-Qahtani, Hanan M. Al-Yousef, Mansour S. Al-Said, AbdelKader E. Ashour, Mohammed Al-Sohaibani, and Syed Rafatullah.  Proanthocyanidin-rich date seed extract protects against chemically induced hepatorenal toxicity.  J Med Food, 18, 280–289 (2015).

145.  Atallah F. Ahmed, Hanan M. Al‑Yousef, Jawaher H. Al‑Qahtani, Mansour S. Al‑Said, AbdelKader E. Ashour, Mohammed Al‑Sohaibani, Syed Rafatullah.  Hepatorenal protective effect of Antistax® against chemically‑induced toxicity.  Pharmacognosy Magazine, 11, S173-S181 (2015).

146. Abdelaaty A. Shahat, Abeer Y. Ibrahim and Mansour S. Alsaid.  Antioxidant capacity and polyphenolic content of seven Saudi Arabian medicinal herbs traditionally used in Saudi Arabia.  Indian Journal of Traditional Knowledge, 14, 28-35 (2015).

147. M. A. Al-Yahya, R. A. Mothana, M. S. Al-Said, M. Al-Dosari, M. Al-Sohaibani, M. K. Parvez, S. Rafatullah.  Protective effect of Citrus medica 'Otroj' extract on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney.  Digest Journal of Nanomaterials and Biostructures, 10, 19-29 (2015).

148.  Mansour AlSaid, Ramzi Mothana, Mohammad Raish, Mohammed Al‑Sohaibani, Mohammed Al-Yahya, Ajaz Ahmad, Mohammed Al‑Dosari, and Syed Rafatullah.  Evaluation of the effectiveness of Piper cubeba extract in the amelioration of CCl4-induced liver injuries and oxidative damage in the rodent model.  BioMed Research International, Volume 2015, Article ID 359358, 11 pages.  http://dx.doi.org/10.1155/2015/359358

149.  Shaza M. Al-Massarani, Ali A. El-Gamal, Mansour S. Al-Said, Sultan S. Al-Lihaibi and Omar A Basoudan.  In vitro cytotoxic, antibacterial and antiviral activities of triterpenes from the red sea sponge, Siphonochalina siphonella. Tropical Journal of Pharmaceutical Research, 14, 33-40 (2015).

more of publication
publications

1.M.S. Al-Said, W.C. Evans; Alkaloids of the leaves of Erythroxylum hypericifolium, J. Pharm. Pharmacol. Suppl.    (1985).

2. M.S. Al-Said, W.C. Evans and R.J. Grout, Alkoids of the Genus…

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