المنشورات و المؤلفات
The study was designed to find out the protein complex(s) associated with HDAC3 in liver cancer using a modified form of affinity purification coupled with a mass spectrometry technique in HepG2 cells. The organ-specific requirement for HDAC1 and...
Series of Schiff bases of valproic acid hydrazide,
N
-valproylglycine hydrazide and
N
-valproyl-4-ami
-
nobenzoyl hydrazide derivatives were synthesized and characterized by IR, NMR (
1
H- and
13
C-NMR) and
elemental analysis. The prepared compounds...
Pulicaria genus belongs to the family Compositae. Some species of this genus have been used in traditional Arab medicine as antispasmodic agent. In this study the Pulicaria glutinosa, which is a wild growing shrub in Saudi Arabia have been explored...
Pulicaria is a genus of flowering plant in the Asteraceae family. It contains over 100 species. In this study the crude extract was prepared from the fresh leaves of P. glutinosa and further fractionated into three solvent to solvent fractions. The...
Background: Valproic acid (VPA) is a potent anticancer and antiangiogenic agent. However, design andsynthesis of chemical derivatives with improved antiangiogenic and anticancer activities are still necessary. Inthis study a library of novel...
Purpose:
To investigate the antiproliferative and apoptotic activity of crude and dichloromethane fraction of A. sieberi against seven cancer cell lines (Colo20, HCT116, DLD, MCF7, Jurkat, HepG2 andL929).
Methods:
sieberi was extracted...
Endophytic microorganisms are fungi or bacteria which live inside plant tissues or organs, without causing them any harmful symptoms. Indeed, since many are also able to produce substances of biotechnological interest, they may protect the plant...
Eight novel N'-(2-oxoindolin-3-ylidene)-2-propylpentane hydrazide-hydrazone derivatives 4a-h were synthesized and fully characterized by IR, NMR ((1)H-NMR and (13)C-NMR), elemental analysis, and X-ray crystallography. The cyto-toxicity and in vitro...
Background: Nanoparticles of gold and silver are offering revolutionary changes in the field of cancer therapy.N-heterocyclic carbene (NHC) metal complexes possess diverse biological activities and are being investigatedas potential chemotherapeutic...
N-Heterocyclic carbene (NHC) metal complexes possess diverse biological activities but have yet to be extensively explored as potential chemotherapeutic agents. We have previously reported the synthesis of a new class of NHC metal complexes N-...
The eastern and southern parts of the Faisalabad city produce considerable quantities of industrial and municipal pollutants, much of which is drained into the River Chenab, reducing the productivity of fauna and flora in the river. This study was...
Kefiran is a functional fermented milk product traditionally used for its beneficial probiotic properties. It exhibits antimicrobial, antioxidant, anti-inflammatory anticancer and different health promoting characteristics. Although kefiran showed...