Factors affecting reactions of trialkylcyanoborates with imidoyl chlorides/trifluoroacetic anhydride

Journal Article

• Publication Work Type: Research
• Publication Online URL: http://www.sciencedirect.com/science/article/pii/S0040402015009072
• Magazine \ Newspaper: Tetrahedron
• Issue Number: 36
• Volume Number: 71
• Pages: 6285-6289

Publication Abstract

Methods for generating tert-alkyl organoboron species are in high demand as they are invaluable intermediates for the synthesis of quaternary carbon centres. Herein we report investigations into generation of tert-alkyl organoboron species using imidoyl chlorides as reagents in the organoboron cyanidation reaction. Although alkenyl side-products predominate in particularly hindered cases, tert-alkyl organoboron species can be successfully generated for less hindered examples.