STUDY ON ACUTE TOXICITY, HAEMATOLOGICAL AND BIOCHEMICAL ALTERATIONS INDUCED BY THE EXPOSURE OF DDT TO CATFISH
Journal Article
Mahboob, Zubair Ahmad*, Khalid A Al-Ghanim, Hmoud F Alkahem Al-Balawi, F Al-Misned, Shahid . 2016
Publication Work Type:
Clarias gariepinus, DDT, Acute concentration, Biochemical parameters, Blood profile
Publication Online URL:
Magazine \ Newspaper:
Fresenius Environmental Bulletin
Issue Number:
12a
Volume Number:
25
Pages:
5935-5943
Publication Abstract:
Healthy and active Clarias gariepinus were
exposed to acute and sub-lethal concentrations of
DDT for a period of 96 hours and 30 days,
respectively. The 96 h LC50 was registered as 1.55
mg/l. It has been observed that protein concentration
was decreased, and the glucose was elevated in the
plasma of treated fish. Sub-lethal DDT exposure has
decreased significantly (P<0.05) the level of
glycogen in muscle and liver. The DDT has caused
a decrease in the counts of erythrocyte (RBC) and
leucocyte (WBC), haematocrit (Hct) values and
concentration of haemoglobin (Hb). Various
hematological indices such as mean corpuscular
volume (MCV), mean corpuscular haemoglobin
(MCH) and mean corpuscular haemoglobin
concentration (MCHC) were also changed. The
concentration of magnesium (Mg) was unchanged
but calcium (Ca) was reduced in the blood of
exposed fish. The glutamic-oxaloacetic
transaminase (GOT) and glutamic-pyruvic
transaminase (GPT) activity was increased in the
DDT treated fish. It has been concluded that these
effects were more pronounced in higher
concentration and in the last period of exposure.
Attachment:
| Attachment | Size |
|---|---|
 study_on_acute_toxicity_haematological.pdf | 460.52 KB |