One-pot synthesis of 2,3,4,5,6-pentasubstituted tetrahydropyrans using lithiation–borylation, allylation and Prins cyclisation reactions

Journal Article

⇑, Adeem Mahmood , Jose Ramón Suárez, Stephen P. Thomas, Varinder K. Aggarwal . 2013

• نوع عمل المنشور: PhD
• رابط المنشور على الويب: Tetrahedron Letters
• رقم الإصدار السنوي: 54
• الصفحات: 49-51

مستخلص المنشور

2,3,4,5,6-Pentasubstituted tetrahydropyrans have been prepared in good yield (42–57%) with excellent dr (>95:5) and er (>95:5) using a one-pot lithiation–borylation, allylation and Prins cyclisation reaction.