Simple and efficient one step synthesis of functionalized flavanones and chalcones.

Journal Article

, A. S. Al-Bogami, U. Karama, A. A. Mousa, M. Khan, S. A. Al-Mazroa and H. Z. Alkhathlan*. . 2012

• المجلة \ الصحيفة: Oriental Journal of Chemistry.
• رقم العدد: 2
• رقم الإصدار السنوي: 28
• الصفحات: 619-626.

مستخلص المنشور

A facile and highly efficient microwave-assisted synthesis of functionalized chalcones and flavanones based on the Claisen-Schmidt condensation reaction is reported. The method describes the synthesis of flavanones in single step with excellent yield and it was revealed that position and number of substituents on acetophenones and aromatic aldehydes played a very crucial and key role in the construction of flavanone derivatives. Among the thirty two synthesized compounds, five chalcones and one flavanone were novel compounds.