Synthesis, structure, theoretical calculations and biological activity of sulfonate active ester new derivatives

Journal Article

, By:Ghazzali, M ; Khattab, SAN; Elnakady, YA ; Al-Mekhlafi, FA ; Al-Farhan, K ; El-Faham, A . 2013

• المجلة \ الصحيفة: JOURNAL OF MOLECULAR STRUCTURE
• رقم الإصدار السنوي: 1046
• الصفحات: 147-152

مستخلص المنشور

Abstract

A series of naphthyl and tolyl sulfonate ester were synthesized and characterized by H NMR. X-ray single crystal diffraction experiments established the molecular structure of three new sulfonate esters derivatives, and spectral data agree with these in solution. The observed hydrogen bonding is discussed on the basis of crystal structural analyses and DFT/MP2 geometry optimization quantum calculations. Antimicrobial activities were screened for selected compounds against three human cancer cell lines and Mosquito Culex pipiens larvae. (c) 2013 Elsevier B.V. All rights reserved.