Association of ABO and Rh blood groups with breast cancer

Journal Article

g, Sultan Ayoub Meoa,⇑, Faryal Suraya b, Badar Jamil c, Fwziah Al Rouq a, Anusha Sultan Meo d, Kamran Sattar e, Mohammad Javed Ansari f, Saleh A. Alasiri . 2017

• رابط المنشور على الويب: Association of ABO and Rh blood groups with breast cancer
• المجلة \ الصحيفة: ScienceDirect-Saudi Journal of Biological Sciences

مستخلص المنشور

Objectives: The aim of this study was to determine the association of ‘‘ABO” and ‘‘Rhesus” blood groups
with incidence of breast cancer.
Methods: In this study, we identified 70 research documents from data based search engines including
‘‘PubMed”, ‘‘ISI-Web of Knowledge”, ‘‘Embase” and ‘‘Google Scholar”. The research papers were selected
by using the primary key-terms including ‘‘ABO blood type”, ‘‘Rhesus” blood type and ‘‘breast cancer”.
The research documents in which ‘‘ABO” and ‘‘Rhesus” blood types and breast cancer was debated were
included. After screening, we reviewed 32 papers and finally we selected 25 research papers which met
the inclusion criteria and remaining documents were excluded.
Results: Blood group ‘‘A” has high incidence of breast cancer (45.88%), blood group ‘‘O” has (31.69%); ‘‘B”
(16.16%) and blood group ‘‘AB” has (6.27%) incidence of breast cancer. Blood group ‘‘A” has highest and
blood group ‘‘AB” has least association with breast cancer. Furthermore, ‘‘Rhesus +ve” blood group has
high incidence of breast cancer (88.31%) and ‘‘Rhesus –ve” blood group has least association with breast
cancer (11.68%).
Conclusion: Blood group ‘‘A” and ‘‘Rhesus +ve” have high risk of breast cancer, while blood type ‘‘AB” and
‘‘Rhesus –ve” are at low peril of breast cancer. Physicians should carefully monitor the females with blood
group ‘‘A” and ‘‘Rh +ve” as these females are more prone to develop breast cancer. To reduce breast cancer
incidence and its burden, preventive and screening programs for breast cancer especially in young
women are highly recommended.