Aphids are important agricultural pests worldwide. Their control is largely based on chemical insecticides. One species that shows important invasive abilities and hostplant- related differences is Therioaphis trifolii (Monell) (Hemiptera: Aphididae). T. trifolii maculata, also known as spotted alfalfa aphid (SAA), can be very injurious to alfalfa crops in certain regions, such as in Saudi Arabia for effective control it is essential to diagnose and monitor the resistance mechanisms in the SAA populations.
Previously, a plant steroid, diosgenin, altered cell cycle distribution and induced apoptosis in human osteosarcoma
cell line. The study objective was to investigate if antiproliferative effect of diosgenin was similar for human colon
cancer (Caco-2) cell. Moreover, this work focused on the mitochondrial pathway. Cells were incubated with diosgenin
Garlic (allium sativum) possesses anti-proliferative properties that can be used in anticancer intervention as promising
cancer chemo-preventive constituent. Diallyl disulfide (DADS) is an oil soluble sulfur organic compound. We investigated
DADS inhibitory activity against colon cancer (Caco-2) cells viability or proliferation. Cells were incubated with DADS at
concentrations, 400μM, 500μM, 600μM and 700μM for 72h at 37°C and 5% CO2. DADS effect was dose-dependently.
Natural compounds have been used to treat cancer because of their low cytotoxicity and less adverse effects. Ginger has long been used in traditional medicine as it contains active phenolic compounds that have antioxidant, anti-cancer, anti-inflammatory, antiangiogenesis and antiartherosclerotic properties. We investigated the inhibitory activity of GO against colon cancer (Caco-2) cells viability or proliferation. Cells were incubated with GO at concentrations, 0.2%, 0.25, 0.3 to 0.35% of the volume of the media for 72 h at 37°C and 5% CO2.
An understanding of the ABO and Rh blood group systems is important for blood transfusions and is also pertinent due to their potential association with certain morbidities and susceptibilities to infections. To investigate the diversity and differentiation of the ABO and Rh loci in Middle Eastern populations, data from twelve representative Middle Eastern populations were analyzed. Six populations were in conformity with Hardy-Weinberg equilibrium at the ABO locus. The pooled heterozygosity at both loci was calculated to be highest in the sample from Jordan and lowest in Bahrain.
Objective: To investigate the radioprotecting ability of the extract of the medicinal plant Holarrhena antidysentrica, especially to protect DNA from gamma- radiation induced damages. Materials and Methods: Hydo-alcoholic extract of dried roots of Holarrhena antidysentrica (HAE) was prepared, freeze dried and stored at 40 C. The DNA of the plasmid pBR322 was exposed to gamma-radiation in presence and absence of HAE and subjected to agarose gel electrophoresis to study radioprotecting ability of the extract under in vitro conditions.
Objective: To investigate the molecular mechanism of anti tumor activity of Clerodendron infortunatum extract (CIE) under in vitro condition. Materials and Methods: The cytotoxic activity of CIE extract was tested on murine tumor cells (Dalton’s lymphoma ascites cells - DLA) and normal mouse cells (splenocytes) by trypan blue dye exclusion assay. The ability of the extract to induce apoptosis was measured via acridine orange and propidium iodide dual staining method.
