Objective: Cape gooseberry (Physalis peruviana L.) belongs to the Solanaceae family.
Physalis has many medicinal properties however, the beneficial effect of physalis in protecting against
neurotoxins has not yet been evaluated. This experimental study investigated the protective effect of
physalis juice against the oxidative damage induced by carbon tetrachloride (CCl4) in the rat brain.
Methods: The degrees of protection by physalis in brain tissues were evaluated by determining the brain levels of lipid
A series of substituted pyridinium candidates 2–11 were synthesized and tested as antimicrobial activities by using 4,9-di(3-methoxyphenyl)-2,7-dioxo-1,2,5,6,7,10-hexahydropyrido[2,3-g]quinoline-3,8-dicarbonitrile (1) as starting material. Treatment of cyanopyridione 1 with ethyl chloroacetate afforded bis-ethyl ester derivative 2, which was fused with anthranilic acid to give oxazin-4-on-3,8-dicarbonitrile derivative 3.
In the process of profiling the secondary metabolites of actinobacteria isolated from the Saudi coastal habitats for production of antibiotics and anti-cancer drugs, the cultures of strain WH1 that was identified as Streptomyces heliomycini exhibited strong antibacterial activity against Staphylococcus aureus. By means of MS and NMR techniques, the active
compounds were characterized as actinomycins X0β, X2 and D, respectively. The research on the productivity of this strain for actinomycins revealed that the highest production of .
Host related variations in helminth egg and coccidian oocyst counts were compared
between a naturally infected endemic population of Farasan gazelle and domestic goats on the
Farasan Islands, Saudi Arabia in April 2009. Both bovid species inhabit and browse in the same
area but no cross-infection could be detected. The prevalence and mean intensity quantified as
the number of eggs and oocysts per gram of faeces were taken as a measure of parasite burdens.
Host related differences in prevalence values of Eimeria spp. were significantly higher in domestic
Invertase (β-D-fructofuranoside fructohydrolase; EC 3.2.1.26) is a highly glycosylated enzyme which hydrolyzes sucrose
to glucose and fructose. Therefore, it finds many applications in food and feed industries. In addition, this enzyme become
more attractive for its potential application in pharmaceutical industries based on its antimicrobial activities and its ability to
The study was designed to assess the antioxidative potential of three dietary antioxidants, vitamin C,
Rosemary (Rosmarinus officinalis) leaf extract (10% carnosic acid) and Amla (Embilica officinalis) fruit
extract (aqueous) on cadmium-induced oxidative stress and the related histopathology of the liver and
kidney of Wistar rats. Cadmium was administered as cadmium chloride (15 mg/kg body weight/day) for
4 weeks with five groups co-treated with the antioxidants, vitamin C (100 mg/kg/day) Rosemary leaf
Cordyceps is one of the components of traditional Chinese medicine. This mushroom becomes worldwide famous due to its significant therapeutic effects on various diseases. Nucleoside like cordycepin, a major bioactive compound from Cordyceps militaris, is commonly known as promising anticancer and antitumor compound. The aim of study is to determine an optimal mixture ratio of solvent-solvent-based extraction method, which is used for extraction of cordycepin, from cultivated Cordyceps militaris DSMZ 23612 fermentation broth.
