The tyrosine kinase inhibitor sunitinib was recently approved for use against gastrointestinal stromal tumors and advanced renal cell carcinoma. Yet, the protective effect of sunitinib against breast cancer has been poorly investigated. In this study, we investigated the antiproliferative and apoptogenic effects of sunitinib and the possible mechanism involved against the MCF7 human breast cancer cell line. Treatment of MCF7 cells with sunitinib caused concentration-dependent cell growth suppression due to apoptosis.
basic physiology of the body systems (cell and tissues, digestive system, cardiovascular, reproductive, endocrine, urinary and nervous system)
Taught in level 4
Foundations of Information Engineering; Information Planning Components; Requirements Engineering; Meta-modeling and Modeling; Method Engineering; Method Engineering Support
The course focuses on the health care management of individuals with acute and chronic health care problems; analysis of manifestations of clinical problems in terms of the physiologic and behavioral mechanisms by which alterations occur is emphasized. The use of different nursing conceptualizations and paradigms for synthesis of theory and practice is further emphasized.
تحرير ضمن المعلومات الشخصية