Omer Fantoukh عمر الفنتوخ CV

 

DR. OMER IBRAHIM FANTOUKH
  • Current Occupation:
    • Assistant professor - Pharmacognosy Department - College of pharmacy - King Saud University
    • Consultant and supervisor of phytochemsitry in Medicinal, Aromatic, and Posionous Plants Research Center (MAPPRS)
    • President of Pharmaceutical Scientists Group (PSG) - Saudi Pharmaceutical Society (Twitter @PSG_SPS)
    • Supervisor of training agreements in college of pharmacy 
    • Co-founder of health corrector project (Twitter @H_Corrector)
  • E-mail Address:

 

EDUCATION
  • Ph.D. in Pharmaceutical Sciences - University of Mississippi Aug 2014 - May 2019
  • Master of health and hospital administration - King Saud University (KSU) - studied for a year and a half 2013 (suspended)
  • Bachelor of pharmacy - (KSU) - Pharmacy Sciences 2011

 

RESEARCH INTERESTS
  • Extraction, fractionation, isolation, and purification of bioactive secondary metabolites with particular emphasis on anticancer agents and herb-drug interaction assessment
  • De novo structure elucidation and characterization of natural product compounds
  • Biosynthetic pathways of chemical classes derived from natural products
  • Synthesis of natural product derivatives based on molecular docking studies
  • Developing validated analytical methods using the isolated markers and hyphenated UPLC-MS technique for chemical fingerprinting and standardization of nutraceuticals and herbal supplements

 

PEER-REVIEWED PUBLICATIONS
  1. Fantoukh, O.I., Wang, Y.H., Parveen, A., Hawwal, M., Al-Hamoud, G., Ali, Z., Chittiboyina, A., Khan, I. (2020) Profiling and Quantification of the Key Phytochemicals from the Drumstick Tree (Moringa oleifera) and Dietary Supplements by UHPLC-PDA-MS. Planta Medica
  2. Alasmari, F., Fantoukh, O.I., Alqahtani, F., & Syed, A. “Nanomaterials combat heavy metals-induced toxicological effects through modulating oxidative stress pathways”. Book entitled “Nanobiotechnology: Mitigation of Abiotic Stress in Plants”. Springer.
  3. Al Yousef, H.M., Abdelaziz, S., Alqahtani, A.S., Hassan, W.H.B., Fantoukh, O.I., El-Sayed, M.A. (2020). Phytochemical Profile, Antioxidant and Cytotoxic Potential of Parkinsonia aculeata L. Growing in Saudi Arabia. Saudi Pharmaceutical Journal
  4. Fantoukh, O.I. (2020). Review of The African and Arabian Moringa Species. Chemistry, Bioactivity, and Therapeutic Applications. Journal of Natural Products
  5. Al-Hamoud, G.A., Orfali, R.S., Takeda, Y., Sugimoto, S., Yamano, Y., Al Musayeib, N.M., Fantoukh, O.I., Amina, M., Otsuka, H., Matsunami, K. (2020) Lasianosides F–I: A New Iridoid and Three New Bis-Iridoid Glycosides from the Leaves of Lasianthus verticillatus (Lour.) Merr.. Molecules
  6. Parveen, A., Ali, Z., Fantoukh, O., Alhusban, M., Wang, W., Chittiboyina, A., Khan, I. A. (2020). Undescribed phenylpropanoid and a dimeric sesquiterpenoid possessing a rare cyclobutane ring from Tinospora sinensis. Natural product research
  7. Osman, A. G., Fantoukh, O., Ali, Z., Raman, V., Ibrahim, M. A., Khan, I. A. (2020). Three undescribed monoterpene rhamnosides from the aerial parts of Vangueria agrestis. Natural Product Research
  8. Fantoukh, O., Albadry, M. A., Parveen, A., Hawwal, M. F., Majrashi, T., Ali, Z. Khan, S. I., Chittiboyina, A., Khan, I. A. (2019). Isolation, Synthesis, and Drug Interaction Potential of Secondary Metabolites Derived from the Miracle Tree (Moringa oleifera) Leaves against CYP3A4 and CYP2D6 Isozymes. Phytomedicine.
  9. Fantoukh, O., Dale, O. R., Parveen, A., Hawwal, M. F., Ali, Z., Manda, V., Chittiboyina, A. G., Viljoen, A. M., Khan, I. A., & Khan, S. I. (2019). Safety Assessment of Phytochemicals Derived from the Globalized South African Rooibos Tea (Aspalathus linearis) Through Interaction with CYP, PXR, and P-gp. Journal of Agricultural and Food Chemistry.
  10. Parveen, A., Wang, Y., Fantoukh, O., Alhusban, M., Raman, V., Ali, Z., Khan, I. (2019). Development of a chemical fingerprint as a tool to distinguish closely related Tinospora species and quantitation of marker compounds. Journal of Pharmaceutical and Biomedical Analysis
  11. Parveen, A., Huang, Y., Fantoukh, O., Alhusban, M., Raman, V., Wang, Y. H., Wang, W., Ali, Z., Khan, I. A. (2019). Rearranged clerodane diterpenoid from Tinospora crispa. Natural product research
  12. Osman, A., Ali, Z., Fantoukh, O., Raman, V., Kamdem, R., & Khan, I. (2018). Glycosides of ursane-type triterpenoid, benzophenone, and iridoid from Vangueria agrestis (Fadogia agrestis) and their anti-infective activities. Natural product research.
  13. Avula, B., Bae, J., Raman, V., Fantoukh, O., Wang, Y., Osman, A., Wang, M., Ali, Z., & Khan, I. (2018). Quantification of Phenolic Compounds from Fadogia agrestis and Dietary Supplements using UHPLC-PDA-MS. Planta Medica.

 

PUBLISHED CONFERENCE ABSTRACTS
  1. Fantoukh, O., Ali, Z., Parveen, A., Viljoen, A., & Khan, I. (2016). Flavonoid C- And O-glycosides from Aspalathus linearis. Planta Medica, 82(05).
  2. Parveen, A., Ali, Z., Fantoukh, O., & Khan, I. (2016). Phytochemical constituents of Tinospora Sinensis. Planta Medica, 82(05)

 

MANUSCRIPTS SUBMITTED/IN PROGRESS
  1. Fantoukh, O., et al. Chemical fingerprint profile and comprehensive quantitative analysis of phenolic compounds from South African rooibos tea (Aspalathus linearis) and dietary supplements using UHPLC-PDA-MS (submitted to Journal of Separation Sceince)
  2. Fantoukh, O., et al. In vitro cytotoxicity and neurotoxicity assessment of the alkaloidal constituents derived from Asimina triloba twigs. (submitted to Toxicology Reports)
  3. Fantoukh, O., et al. Phytochemical Investigation of giant sensitive plant (Mimosa pigra) leaves. (submitted to Biochemical Systematics and Ecology)
  4. Fantoukh, O., et al. Metabolic Profiling and Biological Activities of The Aerial Part of Micromeria imbricata Forssk. Growing in Saudi Arabia (submitted to Saudi Journal of Biological Sciences)
  5. Fantoukh, O., et al. Evaluation of The Chemical Constituents Isolated from Tinospora crispa and Tinospora sinensis. (in process)

 

PRESENTATIONS (ORAL/ POSTER)
  1. Fantoukh, O., Wang, Y., Parveen, A., Ali, Z., Hawwal, M., Khan, S., Chittiboyina, A., Viljoen, A., & Khan, A. Drug interaction potential (CYP-PXR-P-gp) and comprehensive quantitative analysis for phytochemicals derived from the globalized South African rooibos tea (Aspalathus linearis) and dietary supplements using UHPLC-PDA-MS. 19th International Conference on the Sciences of Botanicals. Oxford, MS, USA. Apr 09, 2019
  2. Hawwal, M., Fantoukh, O., Ali, Z., Khan, A. Phytochemical Investigation of Mimosa pigra. 19th International Conference on the Sciences of Botanicals. Oxford, MS, USA. Apr 09, 2019
  3. Osman, A., Fantoukh, O., Ibrahim, M., Zaki, A., Raman, V., Ali, Z., Khan, S., and Khan, A. Monoterpene glycosides from the aerial parts of Vangueria agrestis. 19th International Conference on the Sciences of Botanicals. Oxford, MS, USA. Apr 09, 2019
  4. Parveen, A., Fantoukh, O., Wang, Y., Mir, T., Ashfaq, M., Ali, Z., Raman, V., Khan, I. Phytochemical Investigation, Safety and Quality Assessment of Two Tinospora Species. 19th International Conference on the Sciences of Botanicals. Oxford, MS, USA. Apr 09, 2019
  5. Majrashi, T., Khan, S., Ashpole, N., Zulfiqar, F., Fantoukh, O., Chittiboyina, A., Ali, Z., and Khan, I. Chemical and Biological Evaluations of Asimina triloba. 19th International Conference on the Sciences of Botanicals. Oxford, MS, USA. Apr 09, 2019
  6. Fantoukh, O., Dale, O., Ali, Z., Parveen, A., Manda, V., Khan, S., Chittiboyina, A., Viljoen, A., & Khan, A. Safety assessment on drug interaction potential (CYP-PXR-P-gp) of phytochemicals derived from popular South African rooibos tea (Aspalathus linearis). 22nd School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 12, 2018
  7. Haron, M., Fantoukh, O., Chittiboyina, A., Khan, I., and Khan, S. PXR-mediated induction of CYP enzymes by Chinese club moss Huperzia serrata. 22nd School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 12, 2018
  8. Hawwal, M., Fantoukh, O., Ali, Z., & Khan, I. Phytochemical investigation of Mimosa pigra. 22nd School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 12, 2018
  9. Parveen, A., Maqbool, T., Fantoukh, O., Ali, Z., Wang, Y., Raman, V., Ashfaq, MK., & Khan. I. Isolation of secondary metabolites of Tinospora crispa and Tinospora sinensis and assessment of hepatotoxic potential of major furanoditerpenoids in murine model. 22nd School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 12, 2018
  10. Avula, B., Bae, J., Raman, V., Wang, Y., Fantoukh, O., Osman, A., Wang, M., Ali, Z., & Khan, I. Quantification of iridoid and phenolic compounds from roots and aerial parts of Fadogia agrestis and dietary supplements. Annual Meeting for American Society of Pharmacognosy. Lexington, KY, USA. July 24, 2018
  11. Fantoukh, O., Dale, O., Ali, Z., Parveen, A., Manda, V., Khan, S., Chittiboyina, A., Viljoen, A., & Khan, A. Phytochemicals derived from the popular South African rooibos tea (Aspalathus linearis) species and their drug interaction potential. Annual Meeting for American Society of Pharmacognosy. Lexington, KY, USA. July 24, 2018
  12. Fantoukh, O., Albadry, M., Hawwal, M., Parveen, A., Majrashi, T., Ali, Z., Chittiboyina, A., & Khan, I. Isolation, characterization and synthesis of secondary metabolites derived from the miracle tree (Moringa oleifera) leaves. Annual Meeting for American Society of Pharmacognosy. Lexington, KY, USA. July 23, 2018
  13. Haron, M., Fantoukh, O., Chittiboyina, A., Khan, I., and Khan, S. PXR-mediated induction of CYP enzymes by Chinese club moss Huperzia serrata. 18th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 11, 2018
  14. Hawwal, M., Fantoukh, O., Ali, Z., & Khan, I. Phytochemical investigation of Mimosa pigra. 18th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 11, 2018
  15. Osman, A., Ali, Z., Fantoukh, O., & Khan, I. Chemical constituents from the aerial parts of Vangueria agrestis. 18th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 11, 2018
  16. Parveen, A., Ali, Z., Fantoukh, O., & Khan, I. Exploring the chemical diversity of two species of Tinospora. 8th Annual Graduate Student Council Research Symposium. May 10, 2018
  17. Parveen, A., Ali, Z., Fantoukh, O., Shokoohinia, Y., Wang, Y., Raman, V., & Ikhlas A. Khan. Secondary metabolites of Tinospora sinensis and Tinospora crispa. 18th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 11, 2018
  18. Parveen, A., Ali, Z., Fantoukh, O., & Khan, I. Exploring the chemical diversity of two species of Tinospora. 21st School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 6, 2017
  19. Fantoukh,O., Ali, Z., Parveen, A., & Khan, I. Chemical constituents from Moringa oleifera. 21st School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 6, 2017
  20. Hawwal, M., Fantoukh, O., Ali, Z., & Khan, I. Phytochemical investigation of Mimosa pigra. 21st School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 6, 2017
  21. Parveen, A., Ali, Z., Fantoukh, O., & Khan, I. Exploring the chemical diversity of two species of Tinospora. Annual Meeting for American Society of Pharmacognosy. Portland, OR, USA
  22. Fantoukh,O., Ali, Z., Parveen, A., & Khan, I. Phytochemical constituents from Moringa oleifera. 17th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 5, 2017
  23. Parveen, A., Ali, Z., Fantoukh, O., & Khan, I. Phytochemical constituents of Tinospora Sinensis. 20th School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 7, 2016
  24. Fantoukh, O., Ali, Z., Parveen, A., Viljoen, A., & Khan, I. Flavonoid C- And O-glycosides from Aspalathus linearis. 20th School of Pharmacy Annual Poster Session. Oxford, MS, USA. Oct 7, 2016
  25. Fantoukh, O., Ali, Z., Parveen, A., Viljoen, A., & Khan, I. Flavonoid C- And O-glycosides from Aspalathus linearis. 16th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 5, 2016
  26. Parveen, A., Ali, Z., Fantoukh, O., & Khan, I. Phytochemical constituents of Tinospora Sinensis. 16th International Conference on the Sciences of Botanicals. Oxford, MS, USA. April 5, 2016
  27. Fantoukh, O., Alasmari, F., Asiri, B, Al-amri, Y., Fakeha, A., Algunaim, A. Evaluation of directly compressed tablets prepared from different grades of avicel. Riyadh, SA. Jan 10, 2011

 

EXPERIENCES
  • Teaching Assistant: Pharmacognosy department - college of pharmacy - King Saud University (from 18 December 2012 until 14 May 2019).
  • Pharmacist: Saudi Food and Drug Authority (SFDA) from16 July 2011 until 9 December 2012
  • Pharmacist: King Fahad Medical City (KFMC) from 12 April until 12 July 2011
  • Trainee: Pfizer Company from 17 July to 17 August 2010 

 

PROFESSIONAL MEMBERSHIP AND HONORS
  • Reviewer (Journal of Agricultural and Food Chemistry)
  • Reviewer (Journal of Natural Products)
  • Reviewer (Journal of Food Composition and Analysis)
  • Reviewer (Natural Product Research Journal)
  • Reviewer (Saudi Journal of Biological Sciences)
  • Reviewer (Arabian Journal for Science and Engineering)
  • Reviewer (Journal of Nature and Science of Medicine)
  • Reviewer (Data in Brief)
  • Supervisor of training agreements 2019-2020
  • Educational committee 2019-2020
  • Study plans committee in college of pharmacy 2019-2020
  • Academic committee in college of pharmacy 2019-2020
  • Course specifcations committee 2019-2020: community pharmacy - natural products and phytopharmaceuticals I and II.
  • Department website update committee 2019-2020
  • General Student Travel Grant from American Society of Pharmacognosy
  • Graduate Student Grant, Saudi Arabia Cultural Misssion (SACM)
  • Treasurer (Saudi Student Association at University of Mississippi)
  • Treasurer (Saudi Club in oxford, MS supervised by Saudi Cultural Mission)
  • King Saud University Scholarship
  • Ph.D. in Pharmaceutical Sciences, University of Mississippi (Overall GPA: 3.97/4.00)
  • Rho Chi Society
  • Golden Key International Honor Society
  • Gamma Beta Phi Honor Society
  • The American Society of Pharmacognosy
  • American Chemical Society
  • Saudi Pharmaceutical Society

 

CONFERENCES AND TRAINING COURSES
  • 19th International Conference on The Sciences of Botanicals

Place: Oxford, MS, USA
Date: 8 - 11 Apr 2019

  • LC/MS Sci-Dev Day Seminar Series: Developing And Accelerating Your Mass Spec Expertise By Agilent

Place: Memphis, TN, USA
Date: 6th  Dec 2018

  • Writing in the Sciences by Stanford University

Place: Coursera online
Date: 24 Oct-19 Nov 2018

  • Annual Meeting for American Society of Pharmacognosy

Place: Lexington, KY, USA
Date: 21-25 July 2018

  • 18th International Conference on The Sciences of Botanicals

Place: Oxford, MS, USA
Date: 9-12 Apr 2018

  • 17th International Conference on The Sciences of Botanicals

Place: Oxford, MS, USA
Date: 3-6 Apr 2017

  • Natural Products Training Course Provided By Water

Place: Oxford, MS, USA
Date: 13-17 Mar, 2017

  • 16th International Conference on the Science of Botanicals (ICSB) & 5th Interim American Society of Pharmacognosy (ASP)

Place: Oxford, MS, USA
Date: 11-14 Apr 2016

  • 42nd Annual MALTO Medicinal Chemistry–Pharmacognosy Meeting

Place: Oxford, MS, USA
Date: 17-19 May, 2015

  • 15th International Conference on The Sciences of Botanicals

Place: Oxford, MS, USA
Date: 8-11 Apr, 2015

  • Introduction of European Regulatory Affairs

Place: Cambridge,  UK
Date: Aug, 2012

  • Medication Safety: A Mission for All Symposium

Place: Riyadh, SA
Date: 13-14 Apr, 2010

  • 8th International Saudi Pharmaceutical Conference.

Place: Riyadh, SA
Date: 25-28 Apr, 2010

  • 1st International Cardiovascular Pharmacotherapy Conference and Exhibition.

Place: Riyadh, SA
Date: 12-13 Jan, 2010

 
 
SKILLS
Decision maker – deep thinker – good listener and talker in a diplomatic manner – cooperative and collaborative – time management – self-control – creative – honest – hard worker – active and proactive – good writing, reading and listening in English/Arabic languages – critical thinking and ability to accept constructive criticism – ability to persuade