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Omar Salem Abdullah Al-Attas

Professor

Biochemistry

كلية العلوم
Office NO:2A 59
المنشورات
مقال فى مجلة
1989
تم النشر فى:

Comparative studies on the major feature of insulin receptors in mammalian and non-mammalian liver membranes.

O.S., Al-Attas . 1989

insulin mammalian liver

1. The camel has insulin receptors that by multiple function criteria are very similar to those of the other mammals (rabbit and rat) and non-mammals (chicken and pigeon), with sharp pH dependence to insulin binding at pH 7.2-7.6.
2. Equilibrium binding was faster at higher temperatures (24-37 degrees C) than at lower (4 degrees C).
3. Binding data yielded curvilinear Scatchard plots with half maximal displacement of 125I-insulin at 9 x 10(-9) M, 2.5 x 10(-9) M, 6.3 x 10(-10) M for camel, rabbit, pigeon and chicken respectively, suggesting differences in mammalian and non-mammalian liver membranes.
4. Autoradiogram patterns showed the presence of an identical subunit structure with Mr 74,000 for all membranes studied. Pigeon membrane showed a band with Mr 110,000, the absence of which in other membranes could be due to the degradation factor or the concentration of disuccinimidyl suberate (DSS).

نوع عمل المنشور
Master
رقم المجلد
93,1
مجلة/صحيفة
Comp Biochem Physical
الصفحات
125-133
مزيد من المنشورات
publications

Abstract
Objectives: To assess circulating fetuin A and fetuin B levels in participants with and without Gestational Diabetes Mellitus (GDM) and to find out their correlations with other…

بواسطة Sobhy M Yakout 1, Samira Hussein 1, Omar S Al-Attas 1, Syed D Hussain 1, Gamal M Saadawy 1, Nasser M Al-Daghri 1
2023
publications

Abstract

بواسطة Kaiser Wani 1, Malak N K Khattak 1, Gamal M Saadawy 1, Omar S Al-Attas 1, Majed S Alokail 1, Nasser M Al-Daghri 1
2023
publications

Abstract

بواسطة Sobhy Yakout 1, Fatimah Faqeeh 1, Omar Al-Attas 1, Syed D Hussain 1, Nasser M Al-Daghri 1
2021