Experimental Cassia senna intoxication in Lohmann broiler chicks

مستخلص المنشور: 

The aim of this study was to evaluate the toxic effects of Cassia senna fruits in Lohman broiler chicks.
Chicks fed with diet containing 2 and 5% C. senna fruit for 4 weeks, thereafter the chicks in the two
groups were fed with control diet for 2 weeks. Depression in body weight, weight gain, inefficiency of
feed utilization and anaemia was observed in chicks fed with 2 and 5% C. senna compared with the
control diet. There were significant increase in the serum values of sorbitol dehydrogenase, lactate
dehyrogenase, glutamate dehydrogenase, glutmateoxaloacetate transaminase, acid phosphatase uric
acid and significant decrease in the blood values of haemoglobin concentration (Hb), packed cell
volume (PCV) and red blood corpuscle (RBC) in test chicks were compared to those of the control
group. Liver showed vacuolation of the centrilobular hapatocytes in the two groups. Kidneys showed
degeneration and or necrosis of the epithelial cells of the tubules, scattered lymphoid nodules and
shrinkage of the glomerular tufts. Catarrhal enteritis and focal degeneration of the intestinal mucosa
were observed in test groups. At the end of the period following withdrawal of senna meals the damage
to the vital organs was reduced but neither the hepatocytes nor the cells of the renal tubules had
completely reverted to normal.

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