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Dr. Mosaad Mubarak Alhassan / د.مساعد مبارك الحسن

Assistant Professor

أستاذ مساعد في البصريات وعلوم الرؤية الاكلينيكية

كلية العلوم الطبية التطبيقية
Department of Optometry and Vision Sciences, Buliding number 24, 2nd floor, Office number 2097
publication
Journal Article
2020

Visual processing speed in freezing and non-freezing Parkinson’s disease patients

, Alhassan, Mosaad, Jeffery K. Hovis, and Quincy J. Almeida. . 2020

Introduction

Parkinson's disease patients are usually characterized by body motor dysfunction due to dopaminergic reduction in the central nervous system. Freezing of gait is a motor disorder that affects certain Parkinson's disease patients. However, it is hypothesized that non-motor functions mediated by the cholinergic system are also involved in developing freezing of gait. Visual information processing speed, or inspection time is independent of the motor response, and can be used a reliable measure of the cholinergic system integrity.

Objective

Inspection time can be used to investigate whether Parkinson's disease patients with freezing of gait symptoms have a larger impairment in cholinergic mediated functions than those patients who have no freezing of gait symptoms and healthy controls.

Methods

The inspection time was determined by a simple length discrimination task. Twenty-two Parkinson's disease patients with freezing of gait, 25 Parkinson's disease patients without freezing of gait, and 25 aged matched healthy controls participated in the study.

Results

Based on the log values of IT score, Parkinson's disease patients with freezing of gait symptoms had statistically significant slower inspection times (mean of 1.793 ms) than Parkinson's disease patients without freezing of gait (mean of 1.655 ms) and healthy controls (mean of 1.523 ms). Inspection times for the Parkinson's disease patients without FOG symptoms were also significantly slower than healthy controls.

Conclusion

The results of this study support the hypothesis that the cholinergic system integrity is affected more in Parkinson's disease patients with freezing of gait symptoms.

Publication Work Type
PhD
Issue Number
100060
Magazine \ Newspaper
Clinical Parkinsonism & Related Disorders
more of publication
publications

urpose: Three-dimensional (3D) video games played using virtual reality head-mounted displays (VR-HMDs) are becoming increasingly popular. However, the use of this technology may lead to…

by Mosaad Alhassan, Fatimah Alhamad, Kholoud Bokhary, Ali Almustanyir
2021
publications

Introduction

by Alhassan, Mosaad, Jeffery K. Hovis, and Quincy J. Almeida.
2020
publications

Individuals with Parkinson's disease and convergence insufficiency were assigned vergence training. After two months, average positive fusional vergence increased and average near point of…

by Carolyn M. Machan, Estefania Chriqui, Caroline Law, Benjamin Norman, Mosaad Alhassan, Quincy J. Almeida, Hélène Kergoat, Elizabeth L. Irving
2020