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Ponmurugan Karuppiah

Researcher

Faculty

كلية العلوم
Building 5, 2B61, Department of Botany and Microbiology
publication
Journal Article
2012

Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens.

, Ponmurugan Karuppiah, . 2012

OBJECTIVE:

To evaluate the antibacterial properties of Allium sativum (garlic) cloves and  Zingiber officinale (ginger) rhizomes against multi-drug resistant  clinical pathogens  causing nosocomial infection.

METHODS:

The cloves of garlic and rhizomes of ginger were extracted with 95% (v/v) ethanol. The ethanolic extracts were subjected to antibacterial sensitivity test against  clinical pathogens.

RESULTS:

Anti-bacterial potentials of the extracts of two crude garlic cloves and ginger rhizomes were tested against five gram negative and two gram positive multi-drug resistant bacteria isolates. All the bacterial isolates were susceptible to crude extracts of both plants extracts. Except Enterobacter sp. and Klebsiella sp., all other isolates were susceptible when subjected to ethanolic extracts of garlic and ginger. The highest inhibition zone was observed with garlic (19.45 mm) against  Pseudomonas aeruginosa (P. aeruginosa). The minimal inhibitory concentration was as low as 67.00 µg/mL against P. aeruginosa.

CONCLUSIONS:

Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug resistant microbial diseases and further evaluation is necessary.

Publication Work Type
Phd
Volume Number
2
Issue Number
8
Magazine \ Newspaper
Asian Pacific Journal of Tropical Biomedicine
Pages
597 To 601
more of publication
publications

OBJECTIVE:

To evaluate the antibacterial properties of Allium sativum (garlic) cloves and  Zingiber officinale (ginger) rhizomes against multi-drug …

by Ponmurugan Karuppiah, , Shyamkumar Rajaram
2012