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Shams Tabrez Khan

Assistant Professor

Faculty Member

كلية العلوم
Bulding 5, 2B121

ZnO and TiO2 nanoparticles as novel antimicrobial agents for oral hygiene: a review

Musarrat, Shams Tabrez Khan , Abdulaziz A. Al-Khedhairy, Javed . 2015

Oral cavity is inhabited by more than 25,000 different bacterial phylotypes; some of them cause systemic infections in addition to dental and periodontal diseases. Emergence of multiple antibiotic resistance among these bacteria necessitates the development of alternative antimicrobial agents that are safe, stable, and relatively economic. This review focuses on the significance of metal oxide nanoparticles, especially zinc oxide and titanium dioxide nanoparticles as supplementary antimicrobials for controlling oral infections and biofilm formation. Indeed, the ZnO NPs and TiO2NPs have exhibited significant antimicrobial activity against oral bacteria at concentrations which is not toxic in in vivo toxicity assays. These nanoparticles are being produced at an industrial scale for use in a variety of commercial products including food products. Thus, the application of ZnO and TiO2 NPs as nanoantibiotics for the development of mouthwashes, dental pastes, and other oral hygiene materials is envisaged. It is also suggested that these NPs could serve as healthier, innocuous, and effective alternative for controlling both the dental biofilms and oral planktonic bacteria with lesser side effects and antibiotic resistance.

Volume Number
17
Magazine \ Newspaper
Journal of Nanoparticle Research
Pages
267
more of publication
publications

Envisaging the role of Co in theranautics and biomedicine it is immensely important to evaluate its anti-microbial activity. Hence in this study CoO thin nanosheets (CoO-TNs) were synthesized…

by Shams Tabrez Khan, Rizwan Wahab, Javed Ahmad, Abdulaziz A Al-Khedhairy, Maqsood A Siddiqui, Quaiser Saquib, Bahy A Ali, Javed Musarrat
2015
publications

Oral cavity is inhabited by more than 25,000 different bacterial phylotypes; some of them cause systemic infections in addition to dental and periodontal diseases. Emergence of multiple antibiotic…

by Shams Tabrez Khan , Abdulaziz A. Al-Khedhairy, Javed Musarrat
2015
publications

Copper ferrite nanoparticles (NPs) have the potential to be applied in biomedical fields such as cell labeling and hyperthermia. However, there is a lack of information concerning the toxicity of…

by Ahmad J, Alhadlaq HA, Alshamsan A, Siddiqui MA, Saquib Q, Khan ST, Wahab R, Al-Khedhairy AA, Musarrat J, Akhtar MJ, Ahamed M.
2016