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Shaik Sarfaraz Nawaz

Researcher

Researcher

كلية الطب
Strategic Center for Diabetes Research, College of Medicine, King Saud University
publication
Journal Article
2020

Association of sex hormone binding globulin with gestational age and parity in gestational diabetes mellitus

Abstract
Objective: Recent research on sex hormone binding globulin (SHBG) has emphasized its role in the prediction of gestational diabetes mellitus (GDM) development. SHBG is associated with glucose tolerance status, and its level is regulated by prenatal and perinatal factors during pregnancy. This study aimed to determine the levels of SHBG in pregnant women with normal glucose tolerance and those with GDM in association with parity and gestational age (weeks).
Materials and methods: This cross-sectional study enrolled 218 pregnant women (165 controls and 53 women with GDM). Serum SHBG levels were analyzed using enzyme-linked immunosorbent assay. The association of SHBG with gestational age was assessed using multivariate regression analysis after adjustment for GDM-related risk factors.
Results: Parity sub-group analyses indicated the presence of significant differences in the SHBG levels between nulliparous women in the GDM and control groups (p = .04). Moreover, in the GDM group, SHBG was significantly associated with gestational age beyond the risk factors of GDM.

Publisher Name
The Journal of Maternal-Fetal & Neonatal Medicine
Pages
1-6
more of publication
publications

Abstract

by K Siddiqui, TP George, SS Joy, SS Nawaz,
2020
Published in:
The Journal of Maternal-Fetal & Neonatal Medicine
publications

Metabolomics is rapidly evolving omics technology in personalized medicine, it offers a new avenue for identification of multiple novel metabolic mediators of impaired glucose tolerance and…

by S Chowdhury, SM Faheem, SS Nawaz, K Siddiqui,
2021
Published in:
Personalized Medicine