A Novel Centrosymmetric Fe(III) Complex with Anionic Bis-pyrazolyl-s-triazine Ligand; Synthesis, Structural Investigations and Antimicrobial Evaluations
Saied M. Soliman , Hessa H. Al-Rasheed , Sobhy E. Elsilk and Ayman El-Faham, 2021
Reaction of 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (MBPT) pincer
ligand with FeCl3
in acidic medium (1:1 v/v) afforded the [Fe(BPT)Cl2
(CH3OH)] complex of the
hydrolyzed monobasic ligand: 4,6-bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazin-2(1H)-one (HBPT).
In this complex, the Fe(III) ion is hexacoordinated with one anionic pincer ligand unit (BPT−1),
two chloride ions, and one coordinated methanol molecule. It crystallized in the monoclinic crystal system and centrosymmetric P21/c space group with Z = 2 and unit cell parameters of a = 7.309(2) Å, b = 25.461(8) Å, c = 9.918(3) Å and β = 102.646(7)◦. The structure of this complex is stabilized by C–H . . . Cl intramolecular hydrogen bonding interactions with donor acceptor distances ranging from 3.577(3)–3.609(3) Å while its supramolecular structure is controlled by intermolecular O–H . . . O, O–H . . . N, and C–H . . . Cl hydrogen bonding interactions. Hirshfeld analysis of molecular packing indicates that the percentages of the Cl . . . H, C . . . O, O . . . H, C . . . C, H . . . C, and N . . . H contacts are 21.1, 1.7, 10.2, 2.1, 8.6, and 10.4%, respectively. The nature and relative strength of the different coordination interactions in the [Fe(BPT)Cl2(CH3OH)] complex are discussed based on atoms in molecules theory. Antimicrobial evaluations indicated that the [Fe(BPT)Cl2(CH3OH)] complex showed moderate antibacterial and antifungal activities compared to amoxicillin and ampicillin antibiotics as standard drugs.
Molecular and supramolecular structures of two polymeric and one trinuclear Cd(II) complex with hydralazine-type ligands were presented.
Reaction of 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (MBPT) pincer
ligand with FeCl3
in acidic medium (1:1 v/v) afforded the [Fe(BPT)Cl2
(CH3OH)] complex of…
DMB (Dimethylbarbituric) and DETB (Diethylthiobarbituric) are both barbituric and thiobarbituric acid derivatives respectively, that forms enamines with the Nα amine of amino acids.