Synthesis of a series of diphenyl (arylamino)(pyridin-3-yl)methylphosphonates as potential antimicrobial agents

Series of diphenyl 1-(arylamino)(pyridin-3-yl)methylphosphonates were obtained in high yields from the reactions of nicotinaldehyde with aromatic amines and triphenylphosphite in the presence of titanium tetrachloride as a catalyst. The structures of the synthesized compounds were confirmed by IR, 1H NMR and mass spectral data and their purities were confirmed by elemental analyses.


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