Chitosan-S-triazinyl-bis(2-aminomethylpyridine) and Chitosan- S-triazinyl-bis(8-oxyquinoline) Derivatives: New Reagents for Silver Nanoparticle Preparation and Their Effect of Antimicrobial Evaluation
Abd‑Elkader, Omar H. . 2020
Herein, we described the modification of chitosan with cyanuric chloride as a mediator for preparation of chitosan-s-triazinylbis(
2-aminomethylpyridine) and chitosan-s-triazinyl-bis(8-oxyquinoline) derivatives to be used as reagents for preparation of
silver nanoparticles under ecofriendly conditions. ,ese two reagents are convenient and effective for reduction of silver ions to
silver nanoparticles with particle size less than 10nm that might be suitable for industrial and medicinal applications. ,e
formation and particle size of AgNPs are characterized by transmission electron microscopy (TEM), X-ray diffraction (XRD),
scanning electron microscope (SEM), and energy-dispersive X-ray analysis (EDX). ,e antimicrobial activity of the two modified
chitosan-s-triazine-AgNPs was evaluated against activities against Gram-positive bacteria (M. luteus ATCC 10240 and MRSA
ATCC 43300), Gram-negative bacteria (E. coli ATCC 25922 and P. aeruginosa ATCC 75853), and C. albicans. ,e results showed
that chitosan-s-triazinyl-bis(2-aminomethylpyridine) AgNPs showed high antimicrobial activities against all the tested microorganisms,
while their analogous chitosan-s-triazinyl-bis(8-oxyquinoline) AgNPs showed moderate activities.
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Herein, we described the modification of chitosan with cyanuric chloride as a mediator for preparation of chitosan-s-triazinylbis(
2-aminomethylpyridine) and chitosan-s-triazinyl-bis(8-…